Lomustine
- Generic Name
- Lomustine
- Brand Names
- Ceenu, Gleostine
- Drug Type
- Small Molecule
- Chemical Formula
- C9H16ClN3O2
- CAS Number
- 13010-47-4
- Unique Ingredient Identifier
- 7BRF0Z81KG
- Background
An alkylating agent of value against both hematologic malignancies and solid tumors.
- Indication
For the treatment of primary and metastatic brain tumors as a component of combination chemotherapy in addition to appropriate surgical and/or radiotherapeutic procedures. Also used in combination with other agents as secondary therapy for the treatment of refractory or relapsed Hodgkin's disease.
- Associated Conditions
- Metastatic Brain Tumors, Primary Brain Neoplasm, Refractory Hodgkin Lymphoma
- Associated Therapies
- -
Radiation Therapy With and Without Combination Chemotherapy in Patients With Resected Anaplastic Oligodendroglioma
- Conditions
- First Posted Date
- 2004-01-22
- Last Posted Date
- 2012-07-10
- Target Recruit Count
- 350
- Registration Number
- NCT00002840
- Locations
- ๐ซ๐ท
CHU de la Timone, Marseille, France
๐ซ๐ทCRLCC Nantes - Atlantique, Nantes-Saint Herblain, France
๐ง๐ชHopital Universitaire Erasme, Brussels, Belgium
Methotrexate, Procarbazine, Lomustine, Dexamethasone, and Cytarabine in Treating Patients With Primary CNS Lymphoma
- Conditions
- First Posted Date
- 2003-12-11
- Last Posted Date
- 2017-04-21
- Lead Sponsor
- OHSU Knight Cancer Institute
- Target Recruit Count
- 1
- Registration Number
- NCT00074191
- Locations
- ๐บ๐ธ
Oregon Health & Science University Cancer Institute, Portland, Oregon, United States
Temozolomide, Thalidomide, and Lomustine in Treating Patients With Unresectable Stage III or Stage IV Melanoma
- Conditions
- First Posted Date
- 2003-11-06
- Last Posted Date
- 2013-01-18
- Lead Sponsor
- Memorial Sloan Kettering Cancer Center
- Registration Number
- NCT00072345
- Locations
- ๐บ๐ธ
Memorial Sloan-Kettering Cancer Center, New York, New York, United States
Oral Combination Chemotherapy in Treating Elderly Patients With Intermediate or High-Grade Non-Hodgkin's Lymphomas
- Conditions
- First Posted Date
- 2003-09-24
- Last Posted Date
- 2011-01-17
- Lead Sponsor
- Case Comprehensive Cancer Center
- Target Recruit Count
- 6
- Registration Number
- NCT00003113
- Locations
- ๐บ๐ธ
Ireland Cancer Center at University Hospitals Case Medical Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States
Combination Chemotherapy in Treating Patients With AIDS-Related Hodgkin's Disease
- Conditions
- First Posted Date
- 2003-08-13
- Last Posted Date
- 2010-06-11
- Lead Sponsor
- Case Comprehensive Cancer Center
- Target Recruit Count
- 5
- Registration Number
- NCT00003114
- Locations
- ๐บ๐ธ
Ireland Cancer Center at University Hospitals Case Medical Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States
Intrathecal Radioimmunotherapy, Radiation Therapy, and Chemotherapy After Surgery in Treating Patients With Medulloblastoma
- First Posted Date
- 2003-04-09
- Last Posted Date
- 2020-05-11
- Lead Sponsor
- Memorial Sloan Kettering Cancer Center
- Target Recruit Count
- 6
- Registration Number
- NCT00058370
- Locations
- ๐บ๐ธ
Memorial Sloan-Kettering Cancer Center, New York, New York, United States
๐บ๐ธHerbert Irving Comprehensive Cancer Center at Columbia University Medical Center, New York, New York, United States
Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma
- Conditions
- First Posted Date
- 2003-02-06
- Last Posted Date
- 2014-06-24
- Lead Sponsor
- University of Leicester
- Target Recruit Count
- 316
- Registration Number
- NCT00053872
- Locations
- ๐ซ๐ท
Institut Curie Hopital, Paris, France
๐ฉ๐ชUniversitaets - Kinderklinik Wuerzburg, Wuerzburg, Germany
๐ณ๐ฑAcademisch Medisch Centrum at University of Amsterdam, Amsterdam, Netherlands
Temozolomide Compared to Procarbazine, Lomustine, and Vincristine in Treating Patients With Recurrent Malignant Glioma
- Conditions
- First Posted Date
- 2003-01-27
- Last Posted Date
- 2013-12-18
- Lead Sponsor
- Institute of Cancer Research, United Kingdom
- Target Recruit Count
- 500
- Registration Number
- NCT00052455
- Locations
- ๐ฌ๐ง
Medical Research Council Clinical Trials Unit, London, England, United Kingdom
Surgery, Radiation Therapy, and Chemotherapy With or Without Photodynamic Therapy in Treating Patients With Newly Diagnosed or Recurrent Malignant Supratentorial Gliomas
- Conditions
- First Posted Date
- 2003-01-27
- Last Posted Date
- 2013-11-06
- Lead Sponsor
- Colorado Health Foundation
- Target Recruit Count
- 270
- Registration Number
- NCT00003788
- Locations
- ๐จ๐ฆ
St. Michael's Hospital-Annex, Toronto, Ontario, Canada
๐บ๐ธWestern Pennsylvania Hospital, Pittsburgh, Pennsylvania, United States
๐บ๐ธRocky Mountain Neurological Associates, Englewood, Colorado, United States
Low-Dose Radiation and Combination Chemotherapy Following Surgery in Children With Newly Diagnosed Medulloblastoma
- First Posted Date
- 2003-01-27
- Last Posted Date
- 2019-04-25
- Lead Sponsor
- Children's Hospital of Philadelphia
- Target Recruit Count
- 30
- Registration Number
- NCT00031590
- Locations
- ๐บ๐ธ
Lucile Packard Children's Hospital at Stanford University Medical Center, Palo Alto, California, United States
๐บ๐ธWinship Cancer Institute of Emory University, Atlanta, Georgia, United States
๐บ๐ธChildren's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
Drug Development Updates
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