Overview
Ubidecarenone, also called coenzyme Q10, is a 1,4-benzoquinone. From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number of isoprenyl subunits in its tail. It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative phosphorylation. The ubidecarenone is the coenzyme destined for mitochondrial enzyme complexes involved in oxidative phosphorylation in the production of ATP. It is fundamental for cells that have a high metabolic demand. Ubidecarenone is sold as a dietary supplement and is not FDA approved as a drug - it is not meant to treat, cure or prevent any disease. FDA does not approve this dietary supplements before sold nor regulate the manufacturing process.
Indication
The diet supplements containing ubidecarenone are indicated, as stated in the product label, to assist individuals with cardiovascular complaints including congestive heart failure and systolic hypertension. In the product, ubidecarenone is used to increase the cardiac input as well as for the prevention of several other diseases like Parkinson, fibromyalgia, migraine, periodontal disease and diabetes, based on preclinical studies. It is important to highlight that these products are not FDA approved and it is recommended to use under discretion.
Associated Conditions
- Migraine
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2025/07/31 | Not Applicable | Recruiting | |||
2025/03/04 | Phase 1 | Recruiting | toqa saad mohammed mohammed | ||
2024/12/20 | Phase 4 | Recruiting | |||
2024/10/28 | Not Applicable | Completed | |||
2024/10/01 | Phase 2 | Recruiting | |||
2024/08/15 | Phase 2 | Recruiting | Trio Fertility | ||
2024/05/17 | Early Phase 1 | ENROLLING_BY_INVITATION | |||
2023/10/18 | Early Phase 1 | Not yet recruiting | Shi Yun | ||
2023/05/24 | Phase 2 | Active, not recruiting | |||
2021/08/10 | Early Phase 1 | Withdrawn | AdventHealth Translational Research Institute |
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| Vivera Pharmaceuticals, Inc. | 72380-915 | ORAL | 75 mg in 1 1 | 2/10/2020 | |
| MAS Management Group Inc. | 69677-050 | ORAL | 50 mg in 1 1 | 8/11/2015 | |
| Pure Source, LLC | 65121-301 | ORAL | 50 mg in 1 1 | 11/22/2023 | |
| Nutritional Specialties, Inc. | 83027-0037 | ORAL | 8 [hp_X] in 1 mL | 5/15/2025 | |
| Guangdong Joyan Biological Technology Co.,Ltd | 85779-002 | TOPICAL | 0.02 g in 100 g | 6/10/2025 | |
| Parasitology Center Inc. | 70321-0003 | ORAL | 10 [hp_X] in 1 mL | 5/22/2025 | |
| Oncora Pharma, LLC | 85477-606 | ORAL | 50 mg in 1 1 | 9/5/2025 |
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No HSA approvals found for this drug. | |||||
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| No NMPA approvals found for this drug. | |||||
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| DUBICHINONE CAPSULES | N/A | innex bio-tech limited | N/A | N/A | 2/28/2013 |
| EIQUINON TAB 10MG | N/A | N/A | N/A | 2/5/1990 |
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| MaxN-Fuze Multivitamins | 288444 | Max Health & Living Australia Pty Ltd | Medicine | A | 5/1/2017 |
| Coenzyme Q10 150mg | 306752 | Medicine | A | 7/6/2018 | |
| Swisse Ultiboost High Strength Co-Enzyme Q10 | 304748 | Medicine | A | 6/19/2018 | |
| Thompson's Ultra CoQ10 | 159961 | Medicine | A | 3/9/2009 | |
| Eagle Q10 150 Capsules | 158295 | Medicine | A | 1/5/2009 | |
| CoQ10 Bio-Boost 50mg Vege Cap | 157248 | Medicine | A | 11/26/2008 | |
| Natures Top Prime Medi Vascular and Liver MVL | 302733 | Medicine | A | 5/8/2018 | |
| GO CO-Q10 160mg 1-A-DAY | 292056 | Medicine | A | 7/26/2017 | |
| Top Life Cellenova | 330661 | Medicine | A | 3/3/2020 | |
| Rejufort Heart & Cardiovascular Health | 361471 | Pharmametics Products A Division of Max Biocare Pty Ltd | Medicine | A | 4/12/2021 |
Health Canada Drug Approvals
Approved Product | Company | DIN | Dosage Form | Strength | Market Date |
|---|---|---|---|---|---|
| BIOGARD UBIQUINONE CAP 30MG | sisu inc. | 02065894 | Capsule - Oral | 30 MG | 12/31/1994 |
| COENZYME Q10 80MG | organika health products inc. | 02230696 | Capsule - Oral | 80 MG | 4/3/1997 |
| CO-ENZYME Q10 30MG CAPSULES | alive vitamins | 02231595 | Capsule - Oral | 30 MG | 7/27/1998 |
| COENZYME Q-10 - 30 MG | vita health products inc | 02153149 | Capsule - Oral | 30 MG | 12/31/1995 |
| COENZYME Q10 100MG | prairie naturals | 02244697 | Capsule - Oral | 100 MG | 9/13/2001 |
| VITAMIN E AND COQ10 | wn pharmaceuticals ltd. | 02244047 | Capsule - Oral | 30 MG | 10/1/2001 |
| CO-ENZYME Q10 100MG | natural factors nutritional products ltd. | 02240171 | Capsule - Oral | 100 MG / CAP | 7/12/1999 |
| CO-ENZYME Q-10 | seroyal international inc. | 02165147 | Capsule - Oral | 30 MG / CAP | 12/31/1995 |
| NOW COQ10 100 MG | now foods | 02243515 | Capsule - Oral | 100 MG | 1/10/2006 |
| N.U.T. COMPLEX | abundance naturally ltd | 02242765 | Tablet - Oral | 10 MG | 12/6/2000 |
CIMA AEMPS Drug Approvals
Approved Product | Company | Registration Number | Pharmaceutical Form | Prescription Type | Status |
|---|---|---|---|---|---|
| No CIMA AEMPS (Spain) approvals found for this drug. | |||||
Philippines FDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Philippines FDA approvals found for this drug. | |||||
Saudi SFDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Saudi SFDA approvals found for this drug. | |||||
Malaysia NPRA Drug Approvals
Approved Product | Company | Registration Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Malaysia NPRA approvals found for this drug. | |||||
UK EMC Drug Information
Medicine Name | MA Holder | MA Number | Pharmaceutical Form | Active Ingredient | Authorization Date |
|---|---|---|---|---|---|
| No UK EMC drug information found for this drug. | |||||
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