Coenzyme Q10

Generic Name: Coenzyme Q10

Brand Names: -

Drug Type: Small Molecule

Chemical Formula: C_₅₉H_₉₀O_₄

CAS Number: 303-98-0

Unique Ingredient Identifier: EJ27X76M46

Background: Ubidecarenone, also called coenzyme Q10, is a 1,4-benzoquinone. From its name (Q10), the Q refers to the constitutive quinone group, and 10 is related to the number of isoprenyl subunits in its tail. It is a powerful antioxidant, a lipid-soluble and essential cofactor in mitochondrial oxidative phosphorylation. The ubidecarenone is the coenzyme destined for ...

Indication: The diet supplements containing ubidecarenone are indicated, as stated in the product label, to assist individuals with cardiovascular complaints including congestive heart failure and systolic hypertension. In the product, ubidecarenone is used to increase the cardiac input as well as for the prevention of several other diseases like Parkinson, fibromyalgia...

Associated Conditions: Migraine

Associated Therapies: -

Clinical Trials

CoEnzyme Q10 in Statin Myopathy

Not Applicable

Conditions: Statin Myopathy

Interventions: Drug: Placebo
Drug: CoEnzyme Q10

First Posted Date: 2010-06-09

Last Posted Date: 2012-09-07

Lead Sponsor: Hartford Hospital

Target Recruit Count: 135

Registration Number: NCT01140308

Locations: 🇺🇸
Hartford Hospital, Hartford, Connecticut, United States

Coenzyme Q10 in Older Athletes Treated With Statin Medications

Phase 4

Completed

Conditions: Muscle Weakness
Myalgia
Side Effects of Statins

Interventions: Drug: placebo
Drug: Coenzyme q 10

First Posted Date: 2009-12-04

Last Posted Date: 2012-05-03

Lead Sponsor: Richard Deichmann, MD

Target Recruit Count: 20

Registration Number: NCT01026311

Locations: 🇺🇸
Ochsner, New Orleans, Louisiana, United States

Study of CoQ10 During One Cycle of Doxorubicin Treatment for Breast Cancer

Phase 1

Completed

Conditions: Breast Cancer

Interventions: Drug: CoQ10
Other: CoQ10 Placebo
Drug: Doxorubicin
Drug: Cyclophosphamide

First Posted Date: 2009-09-14

Last Posted Date: 2022-10-17

Lead Sponsor: Columbia University

Target Recruit Count: 7

Registration Number: NCT00976131

Locations: 🇺🇸
Columbia University Medical Center, New York, New York, United States

Coenzyme Q10 in Adult-Onset Ataxia

Phase 1

Completed

Conditions: Sporadic Ataxia

Interventions: Drug: Placebo (sugar pill)
Drug: Coenzyme Q10

First Posted Date: 2009-08-12

Last Posted Date: 2018-07-11

Lead Sponsor: The University of Texas Medical Branch, Galveston

Target Recruit Count: 1

Registration Number: NCT00957216

Locations: 🇺🇸
The Universtity of Texas, Galveston, Galveston, Texas, United States

Study in PRE-manifest Huntington's Disease of Coenzyme Q10 (UbiquinonE) Leading to Preventive Trials (PREQUEL)

Phase 2

Completed

Conditions: Huntington's Disease

Interventions: Drug: CoQ10

First Posted Date: 2009-06-15

Last Posted Date: 2017-09-25

Lead Sponsor: Johns Hopkins University

Target Recruit Count: 90

Registration Number: NCT00920699

Locations: 🇺🇸
Johns Hopkins University, Baltimore, Maryland, United States
🇺🇸
University of California Davis, Sacramento, California, United States
🇺🇸
Colorado Neurological Institute, Englewood, Colorado, United States

and more 10 locations

CoQ10 in Geriatric Bipolar Depression

Not Applicable

Completed

Conditions: Bipolar Depression

Interventions: Drug: CoEnzyme Q10

First Posted Date: 2008-07-22

Last Posted Date: 2014-01-13

Lead Sponsor: Mclean Hospital

Target Recruit Count: 42

Registration Number: NCT00720369

Locations: 🇺🇸
McLean Hospital, Belmont, Massachusetts, United States

Does Coenzyme Q 10 Supplementation Reduce Muscle Pain Caused by Statins? (Cholesterol Lowering Medications)

Not Applicable

Completed

Conditions: Statin Induced Myalgia

Interventions: Drug: Placebo control
Drug: Coenzyme Q 10

First Posted Date: 2008-07-16

Last Posted Date: 2013-01-25

Lead Sponsor: Hadassah Medical Organization

Target Recruit Count: 37

Registration Number: NCT00716612

Locations: 🇮🇱
Hadassah-Hebrew University Medical Center, Jerusalem, Israel

Coenzyme Q10 in Huntington's Disease (HD)

Phase 3

Terminated

Conditions: Huntington's Disease

Interventions: Other: placebo
Drug: coenzyme Q10

First Posted Date: 2008-02-06

Last Posted Date: 2016-03-30

Lead Sponsor: Massachusetts General Hospital

Target Recruit Count: 609

Registration Number: NCT00608881

Locations: 🇺🇸
Emory University, Wesley Woods Center, 1841 Clifton Road NE Room 314, Atlanta, Georgia, United States
🇺🇸
Idaho Elks Rehabilitation Hospital, 600 North Robbins Road, Boise, Idaho, United States
🇺🇸
University of Maryland School of Medicine, 22 South Greene Street, N4 W49-B, Baltimore, Maryland, United States

and more 46 locations

Effects of Coenzyme Q10 on Charcot-Marie-Tooth Disease

Phase 1

Completed

Conditions: Charcot Marie Tooth Disease

Interventions: Dietary Supplement: Coenzyme Q10

First Posted Date: 2007-10-10

Last Posted Date: 2013-07-15

Lead Sponsor: Memorial Medical Center

Target Recruit Count: 23

Registration Number: NCT00541164

Locations: 🇺🇸
John P Murtha Neuroscience and Pain Institute, Johnstown, Pennsylvania, United States

Effects of Coenzyme Q10 in PSP and CBD

Phase 2

Completed

Conditions: Neurological Disorders
Progressive Supranuclear Palsy

First Posted Date: 2007-09-20

Last Posted Date: 2018-06-15

Lead Sponsor: Lahey Clinic

Registration Number: NCT00532571

Locations: 🇺🇸
Lahey Clinic, Burlington, Massachusetts, United States

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