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Sodium chloride

Generic Name
Sodium chloride
Brand Names
Amphenol-40, As 3, Bi-peglyte, Bicart, Bss, Bss Ophthalmic Solution, Cardioplegic, Citrasate, Clinimix E 2.75/5, Colyte, Corvatrol, Dextrose and Electrolyte No. 75, Dianeal, Dianeal Low Calcium 1.5, Dianeal Pd-2/1.5, Extraneal, Eye Stream, Gavilyte-C, Gavilyte-G, Gavilyte-H and Bisacodyl, Gavilyte-N, Golytely, H.E.L.P.bicel, Hemosate Ultra, Hespan, Hizentra, Hyperlyte, Intersol, Isolyte S, Isolyte S pH 7.4, Isoplate, Lactate 1-2-3, Lactated Ringers, Menopur, Moviprep, Muro 128, Naturalyte, Normosol-M, Normosol-R, Nulytely, Nxstage Pureflow, P-Care M, P-Care MG, P-care, P-care X, Peglyte, Phoxillum, Physiolyte, Physioneal 40, Physiosol, Plasma-lyte, Plasma-lyte 148, Plasma-lyte 148 In 5 % Dextrose, Plasma-lyte R, Plasmalyte A, Plegisol, Plenvu, Prismasol, Procalamine 3, Ringers, Sag-M, Sclerodex, Suflave, Tis-U-sol
Drug Type
Small Molecule
Chemical Formula
ClNa
CAS Number
7647-14-5
Unique Ingredient Identifier
451W47IQ8X

Overview

Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular organisms. It is listed on the World Health Organization Model List of Essential Medicines.

Background

Sodium chloride, also known as salt, common salt, table salt or halite, is an ionic compound with the chemical formula NaCl, representing a 1:1 ratio of sodium and chloride ions. Sodium chloride is the primary salt in seawater and in the extracellular fluid of many multicellular organisms. It is listed on the World Health Organization Model List of Essential Medicines.

Indication

This intravenous solution is indicated for use in adults and pediatric patients as a source of electrolytes and water for hydration. Also, designed for use as a diluent and delivery system for intermittent intravenous administration of compatible drug additives.

Associated Conditions

  • Allergic Rhinitis (AR)
  • Corneal Edema
  • Dehydration
  • Dehydration Hypertonic
  • Fluid Loss
  • Hemodilution
  • Hypokalemia
  • Hyponatremia
  • Hypotonic Dehydration
  • Hypovolaemia
  • Increase in Intracranial Pressure (ICP)
  • Increased Intra Ocular Pressure (IOP)
  • Inflammation of the Nasal Mucosa
  • Isotonic Dehydration
  • Metabolic Acidosis
  • Nasal Congestion
  • Nasal irritation
  • Oliguria caused by Acute Renal Failure (ARF)
  • Potassium deficiency
  • Sinusitis
  • Skin Irritation
  • Sodium Depletion
  • Dryness of the nose
  • Hypochloremic state
  • Mild Metabolic acidosis
  • Mild, moderate Metabolic Acidosis

Clinical Trials

FDA Approved Products

Sodium chloride
Manufacturer:Fresenius Kabi USA, LLC
Route:INTRAVENOUS
Strength:225 mg in 50 mL
Approved: 2021/11/18
NDC:65219-226
LACTATED RINGERS AND DEXTROSE
Manufacturer:HF Acquisition Co LLC, DBA HealthFirst
Route:INTRAVENOUS
Strength:600 mg in 100 mL
Approved: 2020/05/21
NDC:51662-1521
Ringers
Manufacturer:Baxter Healthcare Corporation
Route:IRRIGATION
Strength:860 mg in 100 mL
Approved: 2012/06/13
NDC:0338-0104
SODIUM CHLORIDE
Manufacturer:Baxter Healthcare Corporation
Route:INTRAVENOUS
Strength:450 mg in 100 mL
Approved: 2022/07/29
NDC:0338-0164
PEG-3350 and Electrolytes
Manufacturer:Affordable Pharmaceuticals, LLC
Route:ORAL
Strength:5.86 g in 4 L
Approved: 2022/09/28
NDC:10572-101

Singapore Approved Products

BAXTER-LACTATED RINGER’S INJECTION USP
Manufacturer:Baxter Healthcare Philippines, Inc
Form:INFUSION, SOLUTION
Strength:600mg per 100mL
Online:Yes
Approved: 2022/09/14
Approval:SIN16604P
DIANEAL LOW CALCIUM (2.5 mEq/l) PERITONEAL DIALYSIS SOLUTION WITH 1.5% DEXTROSE
Manufacturer:BAXTER HEALTHCARE SA, SINGAPORE BRANCH, BAXTER HEALTHCARE CORPORATION
Form:SOLUTION, STERILE
Strength:538 mg/100 ml
Online:Yes
Approved: 1991/10/14
Approval:SIN06627P
DUOSOL WITHOUT POTASSIUM SOLUTION FOR HAEMOFILTRATION
Manufacturer:B. Braun Avitum AG
Form:SOLUTION, STERILE
Strength:4.21g/1000ml
Online:Yes
Approved: 2019/08/20
Approval:SIN15783P
NUTRIFLEX® OMEGA PLUS EMULSION FOR INFUSION
Manufacturer:B. Braun Melsungen AG
Form:INJECTION, EMULSION
Strength:0.402g/1000ml
Online:Yes
Approved: 2018/04/23
Approval:SIN15468P
DIANEAL PD-2 PERITONEAL DIALYSIS SOLUTION WITH 4.25% DEXTROSE
Manufacturer:BAXTER HEALTHCARE SA, SINGAPORE BRANCH, BAXTER HEALTHCARE CORPN
Form:SOLUTION, STERILE
Strength:538 mg/100 ml
Online:Yes
Approved: 1991/03/27
Approval:SIN05589P

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