Eribulin
- Generic Name
- Eribulin
- Brand Names
- Halaven, Eribulin Baxter, Mevlyq
- Drug Type
- Small Molecule
- Chemical Formula
- C40H59NO11
- CAS Number
- 253128-41-5
- Unique Ingredient Identifier
- LR24G6354G
- Background
Eribulin is a microtubule inhibitor indicated for the treatment of patients with metastatic breast cancer who have previously received at least two chemotherapeutic regimens for the treatment of metastatic disease. Eribulin was isolated from the marine sponge Halichondria okadai. Eribulin is also being investigated for use in the treatment of advanced solid ...
- Indication
For the treatment of patients with metastatic breast cancer who have previously received at least two chemotherapeutic regimens for the treatment of metastatic cancer.
- Associated Conditions
- Metastatic Liposarcoma, Refractory, metastatic Breast cancer, Unresectable Liposarcoma
- Associated Therapies
- -
Trial of Eribulin/Cyclophosphamide or Docetaxel/Cyclophosphamide as Neoadjuvant Therapy in Locally Advanced HER2-Negative Breast Cancer
- Conditions
- Interventions
- First Posted Date
- 2012-02-07
- Last Posted Date
- 2016-11-04
- Lead Sponsor
- SCRI Development Innovations, LLC
- Target Recruit Count
- 76
- Registration Number
- NCT01527487
- Locations
- 🇺🇸
Woodlands Medical Specialists, Pensacola, Florida, United States
🇺🇸Nebraska Methodist Cancer Center, Omaha, Nebraska, United States
🇺🇸Northeast Georgia Medical Center, Gainesville, Georgia, United States
Trial of Eribulin Followed by Doxorubicin & Cyclophosphamide for Her2-negative, Locally Advanced Breast Cancer
- First Posted Date
- 2011-12-23
- Last Posted Date
- 2016-10-03
- Lead Sponsor
- Emory University
- Target Recruit Count
- 7
- Registration Number
- NCT01498588
- Locations
- 🇺🇸
Grady Memorial Hospital, Atlanta, Georgia, United States
🇺🇸Emory University Hospital Midtown, Atlanta, Georgia, United States
🇺🇸Emory University Winship Cancer Institute, Atlanta, Georgia, United States
Post-marketing Surveillance for the Clinical Safety and Effectiveness of Eribulin Mesylate in Patients With Inoperable or Recurrent Breast Cancer (Study HAL01S)
- First Posted Date
- 2011-11-02
- Last Posted Date
- 2023-07-24
- Lead Sponsor
- Eisai Co., Ltd.
- Target Recruit Count
- 963
- Registration Number
- NCT01463891
An Open-label, Multicenter, Phase 2 Study to Evaluate the Efficacy and Safety of Eribulin Mesylate in Previously Treated Subjects With Advanced or Metastatic Soft Tissue Sarcoma (Study E7389-J081-217)
- First Posted Date
- 2011-10-24
- Last Posted Date
- 2016-03-28
- Lead Sponsor
- Eisai Co., Ltd.
- Target Recruit Count
- 52
- Registration Number
- NCT01458249
A Randomized, Open-label, Multicenter, Phase 3 Study to Compare the Efficacy and Safety of Eribulin With Treatment of Physician's Choice in Subjects With Advanced Non-Small Cell Lung Cancer
- Conditions
- Interventions
- First Posted Date
- 2011-10-19
- Last Posted Date
- 2023-06-22
- Lead Sponsor
- Eisai Inc.
- Target Recruit Count
- 540
- Registration Number
- NCT01454934
Eribulin in Combination With Capecitabine for Adjuvant Treatment in Estrogen Receptor-Positive Early Stage Breast Cancer
- Conditions
- Interventions
- First Posted Date
- 2011-09-23
- Last Posted Date
- 2023-06-22
- Lead Sponsor
- Eisai Inc.
- Target Recruit Count
- 77
- Registration Number
- NCT01439282
- Locations
- 🇺🇸
New York Oncology Hematology, P.C., Albany, New York, United States
🇺🇸Arizona Oncology Associates, PC - CASA, Tucson, Arizona, United States
🇺🇸Sciode Medical Associates, PLLC, d.b.a. Eastchester Center, Bronx, New York, United States
A Study of Ramucirumab (IMC-1121B) in Combination With Eribulin Versus Eribulin Alone in Participants With Breast Cancer
- Conditions
- Interventions
- First Posted Date
- 2011-09-02
- Last Posted Date
- 2017-02-06
- Lead Sponsor
- Eli Lilly and Company
- Target Recruit Count
- 141
- Registration Number
- NCT01427933
- Locations
- 🇺🇸
ImClone Investigational Site, Vancouver, Washington, United States
Trial of Eribulin in Patients Who Do Not Achieve Pathologic Complete Response (pCR) Following Neoadjuvant Chemotherapy
- First Posted Date
- 2011-07-26
- Last Posted Date
- 2018-06-15
- Lead Sponsor
- SCRI Development Innovations, LLC
- Target Recruit Count
- 127
- Registration Number
- NCT01401959
- Locations
- 🇺🇸
The Center for Cancer and Blood Disorders, Fort Worth, Texas, United States
🇺🇸Mercy Hospital, Portland, Maine, United States
🇺🇸Texas Health Physician Group, Arlington, Texas, United States
Study of Neoadjuvant Carboplatin, Eribulin and Trastuzumab for Operable HER2 Positive Breast Cancer
- Conditions
- Interventions
- First Posted Date
- 2011-07-07
- Last Posted Date
- 2015-08-28
- Lead Sponsor
- Vector Oncology
- Target Recruit Count
- 12
- Registration Number
- NCT01388647
- Locations
- 🇺🇸
Northwest Georgia Oncology Centers, Marietta, Georgia, United States
🇺🇸Holy Cross Hospital, Fort Lauderdale, Florida, United States
🇺🇸Northeast Georgia Cancer Care, Athens, Georgia, United States
Carboplatin and Eribulin Mesylate in Triple Negative Breast Cancer Patients
- Conditions
- Interventions
- First Posted Date
- 2011-06-14
- Last Posted Date
- 2019-06-07
- Lead Sponsor
- Northwestern University
- Target Recruit Count
- 30
- Registration Number
- NCT01372579
- Locations
- 🇺🇸
Northwestern University, Chicago, Illinois, United States
Drug Development Updates
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