MedPath

Vitamin E

Generic Name
Vitamin E
Brand Names
Mvc-fluoride, Vitafol-one
Drug Type
Small Molecule
Chemical Formula
C29H50O2
CAS Number
59-02-9
Unique Ingredient Identifier
N9PR3490H9

Overview

In 1922, vitamin E was demonstrated to be an essential nutrient. Vitamin E is a term used to describe 8 different fat soluble tocopherols and tocotrienols, alpha-tocopherol being the most biologically active. Vitamin E acts as an antioxidant, protecting cell membranes from oxidative damage. The antioxidant effects are currently being researched for use in the treatment of diseases causing bone loss, cardiovascular diseases, diabetes mellitus and associated comorbidities, eye diseases, inflammatory diseases (including skin conditions), lipid disorders, neurological diseases, and radiation damage. Though this research is so far inconclusive, vitamin E remains a popular supplement and is generally considered safe by the FDA.

Background

In 1922, vitamin E was demonstrated to be an essential nutrient. Vitamin E is a term used to describe 8 different fat soluble tocopherols and tocotrienols, alpha-tocopherol being the most biologically active. Vitamin E acts as an antioxidant, protecting cell membranes from oxidative damage. The antioxidant effects are currently being researched for use in the treatment of diseases causing bone loss, cardiovascular diseases, diabetes mellitus and associated comorbidities, eye diseases, inflammatory diseases (including skin conditions), lipid disorders, neurological diseases, and radiation damage. Though this research is so far inconclusive, vitamin E remains a popular supplement and is generally considered safe by the FDA.

Indication

Vitamin E supplementation is indicated for treatment of vitamin E deficiency which can occur in cystic fibrosis, cholestasis and severe liver disease, abetalipoproteinemia or simply poor diet.

Associated Conditions

  • Vitamin Deficiency

FDA Approved Products

Reaphirm Plant Source DHA
Manufacturer:Everett Laboratories, Inc.
Route:ORAL
Strength:20 [iU] in 1 1
Approved: 2011/11/28
NDC:0642-3010

Singapore Approved Products

NEUROGEN-E TABLET
Manufacturer:UNITED LABORATORIES INC
Form:TABLET, FILM COATED
Strength:100 iu
Online:Yes
Approved: 1996/08/22
Approval:SIN08875P
VITALIPID N ADULT INJECTION
Manufacturer:FRESENIUS KABI AB
Form:INJECTION
Strength:1 iu/ml
Online:Yes
Approved: 1990/11/14
Approval:SIN05208P
VITALIPID N INFANT INJECTION
Manufacturer:FRESENIUS KABI AB
Form:INJECTION
Strength:0.7 iu/ml
Online:Yes
Approved: 1990/11/14
Approval:SIN05207P
CERNEVIT FOR INJECTION
Manufacturer:FAREVA PAU 1 (Sub-contractor), Baxter S.A.
Form:INJECTION, POWDER, FOR SOLUTION
Strength:11.2 iu/vial
Online:Yes
Approved: 2002/06/05
Approval:SIN11975P

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