Voriconazole
- Generic Name
- Voriconazole
- Brand Names
- Vfend, Voriconazole Hikma (previously Voriconazole Hospira), Voriconazole Accord
- Drug Type
- Small Molecule
- Chemical Formula
- C16H14F3N5O
- CAS Number
- 137234-62-9
- Unique Ingredient Identifier
- JFU09I87TR
- Background
Voriconazole (Vfend, Pfizer) is a triazole antifungal medication used to treat serious fungal infections. It is used to treat invasive fungal infections that are generally seen in patients who are immunocompromised. These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections. The increased affinity of voriconazole for 14-alpha ...
- Indication
For the treatment of esophageal candidiasis, cadidemia, invasive pulmonary aspergillosis, and serious fungal infections caused by Scedosporium apiospermum and Fusarium spp.
- Associated Conditions
- Aspergillosis of the Central Nervous System, Aspergillosis of the Liver, Candidemia, Candidiasis, Coccidioidomycosis, Endocarditis caused by Aspergillus, Esophageal Candidiasis, Fungal Infections, Fungal meningitis caused by Exserohilum Infection, Fusarium infection, Histoplasmosis, Invasive Aspergillosis, Osteomyelitis caused by Aspergillus, Penicillium marneffei infection, Peritonitis caused by Aspergillus, Scedosporium Infection, Sinusitis aspergillus, Aspergillus endophthalmitis, Refractory Oral Candidiasis
- Associated Therapies
- -
Clinical Study of AK1820 (Isavuconazonium Sulfate) for the Treatment of Deep Mycosis
- First Posted Date
- 2018-03-21
- Last Posted Date
- 2021-05-14
- Lead Sponsor
- Asahi Kasei Pharma Corporation
- Target Recruit Count
- 103
- Registration Number
- NCT03471988
- Locations
- 🇯🇵
Research site, Nagasaki, Japan
The Study of Voriconazole Trough Level in the First Two Weeks After Administration in King Chulalongkorn Memorial Hospital.
- Conditions
- Interventions
- First Posted Date
- 2017-08-24
- Last Posted Date
- 2017-08-24
- Lead Sponsor
- Chulalongkorn University
- Target Recruit Count
- 92
- Registration Number
- NCT03260634
- Locations
- 🇹🇭
Chulalongkorn university, Bangkok, Thailand
Registry of Patients Treated With Systemic Mold-Active Triazoles
- Conditions
- Interventions
- First Posted Date
- 2017-02-28
- Last Posted Date
- 2024-10-21
- Lead Sponsor
- Astellas Pharma Global Development, Inc.
- Target Recruit Count
- 2015
- Registration Number
- NCT03066011
- Locations
- 🇺🇸
Emory University, Atlanta, Georgia, United States
🇺🇸University of Arizona, Tucson, Arizona, United States
🇺🇸Stanford Health Care, Palo Alto, California, United States
Phenotypic Drug Probes as Predictors of Drug-drug Interactions With Tacrolimus
- Conditions
- Interventions
- First Posted Date
- 2015-10-15
- Last Posted Date
- 2019-08-22
- Lead Sponsor
- Universitaire Ziekenhuizen KU Leuven
- Target Recruit Count
- 24
- Registration Number
- NCT02576366
- Locations
- 🇧🇪
University Hospitals Leuven, Leuven, Vlaams-Brabant, Belgium
Concentrations of Voriconazole in Blood and BAL-fluid After Inhalation and Oral Administration
- First Posted Date
- 2015-03-24
- Last Posted Date
- 2017-05-09
- Lead Sponsor
- University of Aarhus
- Target Recruit Count
- 12
- Registration Number
- NCT02396225
- Locations
- 🇩🇰
Aarhus University Hospital, Aarhus C, Denmark
Interaction Study of Ibrutinib and Cytochrome P450 (CYP) 3A Inhibitors in Participants With B-cell Malignancy
- Conditions
- Interventions
- First Posted Date
- 2015-03-06
- Last Posted Date
- 2017-06-26
- Lead Sponsor
- Janssen Research & Development, LLC
- Target Recruit Count
- 26
- Registration Number
- NCT02381080
Amphotericin-B and Voriconazole for Pulmonary Blastomycosis
- First Posted Date
- 2014-11-05
- Last Posted Date
- 2020-09-29
- Lead Sponsor
- University of Manitoba
- Target Recruit Count
- 2
- Registration Number
- NCT02283905
- Locations
- 🇨🇦
St. Boniface General Hospital, Winnipeg, Manitoba, Canada
Voriconazole for IPA in Chinese Patients With COPD
- First Posted Date
- 2014-09-09
- Last Posted Date
- 2014-09-09
- Lead Sponsor
- Red Cross Hospital, Hangzhou, China
- Target Recruit Count
- 40
- Registration Number
- NCT02234739
- Locations
- 🇨🇳
Hangzhou Red Cross Hospital, Hangzhou, Zhejiang, China
MT2013-37R: Voriconazole Monitoring in Pediatric Stem Cell Transplant Patients
- First Posted Date
- 2014-08-28
- Last Posted Date
- 2019-04-29
- Lead Sponsor
- Masonic Cancer Center, University of Minnesota
- Target Recruit Count
- 66
- Registration Number
- NCT02227797
- Locations
- 🇺🇸
University of Minnesota Medical Center, Fairview, Minneapolis, Minnesota, United States
Assessing the Safety and Efficacy of MK-5592 (Posaconazole) in Japanese Participants With Fungal Infection (MK-5592-101)
- First Posted Date
- 2014-07-02
- Last Posted Date
- 2021-01-28
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Target Recruit Count
- 116
- Registration Number
- NCT02180165
Drug Development Updates
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