Altretamine
生产企业:Eisai inc
Altretamine is an antineoplastic agent used in palliative treatment of persistent or recurrent ovarian cancer.
Altretamine is an antineoplastic agent used in palliative treatment of persistent or recurrent ovarian cancer.
The precise mechanism by which altretamine exerts its cytotoxic effect is unknown although it is classified as an alkylating anti-neoplastic agent. Through this mechanism, the drug is metabolized into alkylating agents by N-demethylation. These alkylating species consequently damage tumor cells.
For use as a single agent in the palliative treatment of patients with persistent or recurrent ovarian cancer following first-line therapy with a cisplatin and/or alkylating agent-based combination.
每项发明一条,涵盖美国、欧洲、PCT 与中国的同族专利。