Sumatriptan
- Generic Name
- Sumatriptan
- Brand Names
- Imitrex, Onzetra, Sumavel, Tosymra, Treximet, Zembrace
- Drug Type
- Small Molecule
- Chemical Formula
- C14H21N3O2S
- CAS Number
- 103628-46-2
- Unique Ingredient Identifier
- 8R78F6L9VO
- Background
Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches. Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines. Sumatriptan was granted FDA approval on 28 December 1992.
- Indication
A combination sumatriptan and naproxen tablet is indicated for the treatment of migraines with or without auras in patients 12 years of age and older. Sumatriptan nasal powder, nasal spray, subcutaneous injection, and tablets are indicated to treat migraines with or without auras in adults. One of the subcutaneous formulations of sumatriptan is also indicate...
- Associated Conditions
- Acute Migraine, Acute Cluster headaches
- Associated Therapies
- -
Migraine Attack Treatment Response Molecular and Clinical BiOmarkers (MAMBO) Phase I
- First Posted Date
- 2024-07-16
- Last Posted Date
- 2024-10-28
- Target Recruit Count
- 108
- Registration Number
- NCT06503848
- Locations
- 🇪🇸
Hospital Universitari Vall d'Hebron, Barcelona, Spain
Influence of Ubrogepant and Sumatriptan on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin
- First Posted Date
- 2022-12-16
- Last Posted Date
- 2023-03-28
- Lead Sponsor
- Universitaire Ziekenhuizen KU Leuven
- Target Recruit Count
- 20
- Registration Number
- NCT05654298
- Locations
- 🇧🇪
Center for Clinical Pharmacology, Leuven, Belgium
Effect of Sumatriptan on Levcromakalim-Induced Symptoms in Individuals With Migraine
- Conditions
- Interventions
- First Posted Date
- 2022-01-27
- Last Posted Date
- 2022-01-27
- Lead Sponsor
- Danish Headache Center
- Target Recruit Count
- 20
- Registration Number
- NCT05211050
- Locations
- 🇩🇰
Danish Headache Centre, Glostrup, Zealand, Denmark
Mirtazapine vs Sumatriptan in the Treatment of Postdural Puncture Headache
- First Posted Date
- 2021-11-05
- Last Posted Date
- 2024-01-22
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 210
- Registration Number
- NCT05108688
- Locations
- 🇪🇬
Ain-Shams University Hospitals, Cairo, Egypt
Drug-Drug Interaction Study of Evobrutinib and Transporter Substrates
- Conditions
- Interventions
- First Posted Date
- 2021-10-01
- Last Posted Date
- 2022-01-11
- Lead Sponsor
- Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
- Target Recruit Count
- 40
- Registration Number
- NCT05064488
- Locations
- 🇩🇪
Nuvisan GmbH, Neu-Ulm, Germany
A STUDY TO EVALUATE THE EFFECT OF PF-06651600 ON PHARMACOKINETICS OF SINGLE DOSE SUMATRIPTAN IN HEALTHY PARTICIPANTS.
- First Posted Date
- 2020-04-21
- Last Posted Date
- 2020-09-03
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 10
- Registration Number
- NCT04355845
- Locations
- 🇺🇸
New Haven Clinical Research Unit, New Haven, Connecticut, United States
PACAP38 Induced Headache, Migraine and Flushing in Patients With Migraine
- Conditions
- Interventions
- First Posted Date
- 2019-03-19
- Last Posted Date
- 2020-06-22
- Lead Sponsor
- Danish Headache Center
- Target Recruit Count
- 37
- Registration Number
- NCT03881644
- Locations
- 🇩🇰
DanishHC, Glostrup, Denmark
PACAP38 Induced Headache and Rosacea-like Symptoms in Patients With Rosacea
- First Posted Date
- 2019-03-18
- Last Posted Date
- 2020-03-26
- Lead Sponsor
- Danish Headache Center
- Target Recruit Count
- 38
- Registration Number
- NCT03878784
- Locations
- 🇩🇰
DanishHC, Glostrup, Denmark
Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants
- Conditions
- Interventions
- Drug: Tranexamic acid (TXA)Drug: HydrocodoneDrug: labetalolDrug: metforminDrug: nifedipineDrug: oxycodoneDrug: clindamycinDrug: azithromycinDrug: escitalopramDrug: sertralineDrug: CiprofloxacinDrug: ondansetronDrug: DoxycyclineDrug: LevofloxacinDrug: MethylphenidateDrug: CitalopramDrug: SumatriptanDrug: CyclobenzaprineDrug: FurosemideDrug: RosuvastatinDrug: GabapentinDrug: HydrochlorothiazideDrug: HydroxyureaDrug: TrazodoneDrug: TopiramateDrug: ValganciclovirDrug: RemdesivirDrug: VenlafaxineDrug: VerapamilDrug: FluvoxamineDrug: AnakinraDrug: TocilizumabDrug: AmoxicillinDrug: BupropionDrug: BuprenorphineDrug: LevetiracetamDrug: ParoxetineDrug: Duloxetine
- First Posted Date
- 2018-04-27
- Last Posted Date
- 2024-12-17
- Lead Sponsor
- Duke University
- Target Recruit Count
- 1600
- Registration Number
- NCT03511118
- Locations
- 🇺🇸
Northwestern University, Chicago, Illinois, United States
🇺🇸Ann and Robert H. Lurie Childrens Hospital of Chicago, Chicago, Illinois, United States
🇺🇸Loma Linda University Health, Loma Linda, California, United States
A Study of Lasmiditan When Given With Sumatriptan in Healthy Participants
- Conditions
- Interventions
- First Posted Date
- 2017-10-16
- Last Posted Date
- 2019-11-27
- Lead Sponsor
- Eli Lilly and Company
- Target Recruit Count
- 40
- Registration Number
- NCT03310411
- Locations
- 🇺🇸
Covance Daytona Beach, Daytona Beach, Florida, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.