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Sumatriptan

Generic Name
Sumatriptan
Brand Names
Imitrex, Onzetra, Sumavel, Tosymra, Treximet, Zembrace
Drug Type
Small Molecule
Chemical Formula
C14H21N3O2S
CAS Number
103628-46-2
Unique Ingredient Identifier
8R78F6L9VO

Overview

Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches. Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines. Sumatriptan was granted FDA approval on 28 December 1992.

Background

Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches. Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines. Sumatriptan was granted FDA approval on 28 December 1992.

Indication

A combination sumatriptan and naproxen tablet is indicated for the treatment of migraines with or without auras in patients 12 years of age and older. Sumatriptan nasal powder, nasal spray, subcutaneous injection, and tablets are indicated to treat migraines with or without auras in adults. One of the subcutaneous formulations of sumatriptan is also indicated to treat cluster headaches in adults, while the other subcutaneous formulation is not.

Associated Conditions

  • Acute Migraine
  • Acute Cluster headaches

FDA Approved Products

sumatriptan succinate
Manufacturer:A-S Medication Solutions
Route:ORAL
Strength:25 mg in 1 1
Approved: 2020/11/02
NDC:50090-5939
SUMATRIPTAN
Manufacturer:Prasco Laboratories
Route:SUBCUTANEOUS
Strength:6 mg in 0.5 mL
Approved: 2021/07/09
NDC:66993-084
IMITREX
Manufacturer:GlaxoSmithKline LLC
Route:NASAL
Strength:5 mg in 1 1
Approved: 2024/03/22
NDC:0173-0524
Sumatriptan
Manufacturer:NuCare Pharmaceuticals,Inc.
Route:ORAL
Strength:50 mg in 1 1
Approved: 2023/10/20
NDC:68071-3525
SUMATRIPTAN
Manufacturer:Padagis Israel Pharmaceuticals Ltd
Route:NASAL
Strength:20 mg in 1 1
Approved: 2022/09/01
NDC:45802-598

Singapore Approved Products

IMIGRAN INJECTION 6 mg/0.5 ml
Manufacturer:GLAXO OPERATIONS UK LTD (TRADING AS GLAXO WELLCOME OPERATIONS)
Form:INJECTION
Strength:6 mg/0.5 ml
Online:Yes
Approved: 1991/12/26
Approval:SIN06744P
SUMATRAN TABLET 50MG
Manufacturer:Salutas Pharma GmbH
Form:TABLET
Strength:50mg
Online:Yes
Approved: 2009/06/26
Approval:SIN13667P
IMIGRAN TABLET 50 mg
Manufacturer:Delpharm Poznań S.A.
Form:TABLET, FILM COATED
Strength:50 mg( Equivalent to 70mg as Succinate)
Online:Yes
Approved: 1995/10/26
Approval:SIN08419P
SUMASON TABLETS 50MG
Manufacturer:Unison Pharmaceuticals Pvt. Ltd.
Form:TABLET, FILM COATED
Strength:50mg
Online:Yes
Approved: 2025/02/12
Approval:SIN17179P

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