Picrotoxin
- Generic Name
- Picrotoxin
- Drug Type
- Small Molecule
- Chemical Formula
- C30H34O13
- CAS Number
- 124-87-8
- Unique Ingredient Identifier
- ZLT174DL7U
Overview
A noncompetitive antagonist at GABA-A receptors and thus a convulsant. Picrotoxin blocks the gamma-aminobutyric acid-activated chloride ionophore. Although it is most often used as a research tool, it has been used as a CNS stimulant and an antidote in poisoning by CNS depressants, especially the barbiturates. [PubChem]
Background
A noncompetitive antagonist at GABA-A receptors and thus a convulsant. Picrotoxin blocks the gamma-aminobutyric acid-activated chloride ionophore. Although it is most often used as a research tool, it has been used as a CNS stimulant and an antidote in poisoning by CNS depressants, especially the barbiturates. [PubChem]
Indication
Used internally for relieving respiratory distress. Also for use as an antidote in poisoning by CNS depressants, especially barbiturates.
Associated Conditions
No associated conditions information available.
Clinical Trials
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No clinical trials found
No clinical trials found for this drug
FDA Approved Products
Product Name | Manufacturer | Route | Strength | Approved | NDC Code |
|---|---|---|---|---|---|
ORAL | 16 [hp_X] in 1 mL | 2025/04/08 | 75053-0005 |
EMA Approved Products
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No EMA products found
No EMA products found for this drug
HSA Approved Products
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No HSA products found
No HSA products found for this drug
NMPA Approved Products
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No NMPA products found
No NMPA products found for this drug
PPB Approved Products
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No PPB products found
No PPB products found for this drug
TGA Approved Products
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No TGA products found
No TGA products found for this drug