Obiltoxaximab (Anthim)

概览

Obiltoxaximab is a monoclonal antibody used for prophylaxis or treatment of inhalational anthrax.

作用机制

ETI-204 is an affinity-enhanced, de-immunized antibody, which means that its ability to bind to its target pathogen has been strengthened and that elements that might cause an immune response have been removed. ETI-204 targets and binds to Protective Antigen, which prevents the anthrax toxins from binding to and entering the cells in the body, thereby preventing death.

适应症

Investigated for use/treatment in anthrax exposure, bacterial infection, crohn's disease, and graft versus host disease.

• Inhalational Anthrax