Yohimbine

Overview

A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.

Indication

Indicated as a sympatholytic and mydriatic. Impotence has been successfully treated with yohimbine in male patients with vascular or diabetic origins and psychogenic origins.

Associated Conditions

No associated conditions information available.

Clinical Trials

Title	Posted	Study ID	Phase	Status	Sponsor
Cannabinoids and Biological Reactivity to Stress	2024/05/28	NCT06430580	Early Phase 1	Recruiting	Florida State University
The Role of the Noradrenergic System in the Nonmotor Symptoms of Parkinson's Disease	2020/04/15	NCT04346394	Early Phase 1	Withdrawn	Nathaniel M. Robbins
Effects of Pharmacological Stress and rTMS on Executive Function in Opioid Use Disorder	2020/01/18	NCT04231708	Phase 2	Not yet recruiting	Wayne State University
rTMS of Limbic Circuitry in Stress Modulation in Healthy Volunteers	2019/11/29	NCT04180969	Phase 2	Withdrawn	Wayne State University
Using rTMS to Explore Neural Mechanisms of Stress-Induced Opioid Use	2019/11/29	NCT04181515	Phase 2	Withdrawn	Wayne State University
Investigation of Nicotine Seeking Behavior in Current Smokers	2018/09/13	NCT03670212	Phase 1	Completed	Wayne State University
Effects of Stress and Drug-cue Exposure (SCM)	2017/05/16	NCT03154567	Phase 1	Completed	Wayne State University
Effects of Melatonin to Reduce Nocturnal Hypertension in Patients With Neurogenic Orthostatic Hypotension	2016/11/15	NCT02963181	Early Phase 1	Terminated	Lawson Health Research Institute
Influence of the Noradrenergic System on the Formation of Intrusive Memories	2015/09/04	NCT02541071	Not Applicable	Completed	Charite University, Berlin, Germany
Noradrenergic Activity, Cognition and Major Depressive Disorder	2015/06/12	NCT02470026	Not Applicable	Completed	Charite University, Berlin, Germany

FDA Drug Approvals

Approved Product	Manufacturer	NDC Code	Route	Strength	Effective Date
No FDA approvals found for this drug.

EMA Drug Approvals

Approved Product	Authorization Holder	Status	Issued Date
No EMA approvals found for this drug.

HSA Drug Approvals

Approved Product	Manufacturer	Approval Number	Dosage Form	Strength	Approval Date
No HSA approvals found for this drug.

NMPA Drug Approvals

Approved Product	Company	Approval Number	Drug Type	Dosage Form	Approval Date
No NMPA approvals found for this drug.

PPB Drug Approvals

Approved Product	Registration No.	Company	Licence No.	Strength	Registration Date
No PPB approvals found for this drug.

TGA Drug Approvals

Approved Product	ARTG ID	Sponsor	Registration Type	Status	Registration Date
No TGA approvals found for this drug.

Health Canada Drug Approvals

Approved Product	Company	DIN	Dosage Form	Strength	Market Date
YOHIMBINE TAB 5.4MG	odan laboratories ltd	01901885	Tablet - Oral	5.4 MG	12/31/1991
YOHIMBINE HCL 5.4MG	odan laboratories ltd	01954342	Tablet - Oral	5.4 MG	9/9/1996
YOHIMBINE TAB 2MG	welcker-lyster ltd., division of technilab inc.	00206202	Tablet - Oral	2 MG	12/31/1951
YOHIMBINE TAB 6MG	rougier pharma division of ratiopharm inc	00843512	Tablet - Oral	6 MG	12/31/1990
YOHIMBINE HYDROCHLORIDE TAB 2MG	odan laboratories ltd	00885533	Tablet - Oral	2 MG	12/31/1992
YOHIMBINE-ODAN 6MG	odan laboratories ltd	01985604	Tablet - Oral	6 MG	12/31/1992
YOHIMBINE HYDROCHLORIDE TABLETS 5.4MG	tanta pharmaceuticals inc	02049155	Tablet - Oral	5.4 MG	12/31/1994
YOCON TABLET 5.4MG	palisades pharmaceuticals inc.	00795283	Tablet - Oral	5.4 MG	12/31/1988
YOHIMBINE HCL 2MG	odan laboratories ltd	01954504	Tablet - Oral	2 MG	12/31/1992

CIMA AEMPS Drug Approvals

Approved Product	Company	Registration Number	Pharmaceutical Form	Prescription Type	Status
No CIMA AEMPS (Spain) approvals found for this drug.

Philippines FDA Drug Approvals

Approved Product	Company	License Number	Dosage Form	Strength	Approval Date
No Philippines FDA approvals found for this drug.

Saudi SFDA Drug Approvals

Approved Product	Company	License Number	Dosage Form	Strength	Approval Date
No Saudi SFDA approvals found for this drug.

Malaysia NPRA Drug Approvals

Approved Product	Company	Registration Number	Dosage Form	Strength	Approval Date
No Malaysia NPRA approvals found for this drug.

UK EMC Drug Information

Medicine Name	MA Holder	MA Number	Pharmaceutical Form	Active Ingredient	Authorization Date
No UK EMC drug information found for this drug.

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