Lacidipine

Generic Name
Lacidipine
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C26H33NO6
CAS Number
103890-78-4
Unique Ingredient Identifier
260080034N
Background

Lacidipine is a lipophilic dihydropyridine calcium antagonist with an intrinsically slow onset of activity. Due to its long duration of action, lacidipine does not lead to reflex tachycardia . It displays specificity in the vascular smooth muscle, where it acts as an antihypertensive agent to dilate peripheral arterioles and reduce blood pressure. Compared t...

Indication

Indicated for the treatment of hypertension either alone or in combination with other antihypertensive agents, including β-adrenoceptor antagonists, diuretics, and ACE-inhibitors .

Associated Conditions
Hypertension
Associated Therapies
-

Tolerability and Pharmacokinetics of Telmisartan in Combination With Lacidipine in Healthy Male Subjects

Phase 1
Completed
Conditions
Interventions
First Posted Date
2014-08-18
Last Posted Date
2014-08-18
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
27
Registration Number
NCT02218684

Tolerability and Pharmacokinetics of Lacidipine With and Without the Co-administration of Telmisartan in Female and Male Healthy Subjects

Phase 1
Completed
Conditions
Interventions
First Posted Date
2014-07-30
Last Posted Date
2014-08-06
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
26
Registration Number
NCT02203500

Lacidipine in Medical Practice in Patients With Mild to Moderate Essential Hypertension

Phase 3
Completed
Conditions
Interventions
First Posted Date
2014-06-27
Last Posted Date
2014-07-14
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
53
Registration Number
NCT02177331

Lacidipine In Mild To Moderate Essential Hypertension Patients With Type 2 Diabetes In Korea

First Posted Date
2006-05-24
Last Posted Date
2010-08-16
Lead Sponsor
GlaxoSmithKline
Registration Number
NCT00328965
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