Entecavir

Generic Name
Entecavir
Brand Names
Baraclude, Entecavir Viatris (previously Entecavir Mylan), Entecavir Accord
Drug Type
Small Molecule
Chemical Formula
C12H15N5O3
CAS Number
142217-69-4
Unique Ingredient Identifier
NNU2O4609D
Background

Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection. It is marketed under the trade name Baraclude (BMS).
...

Indication

For the treatment of chronic hepatitis B virus infection in adults with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease.

Associated Conditions
Chronic Hepatitis B Infection
Associated Therapies
-

A Study of ALG-000184 Drug to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Single and Multiple Doses in Healthy Volunteers and CHB Subjects

First Posted Date
2020-09-02
Last Posted Date
2023-04-28
Lead Sponsor
Aligos Therapeutics
Target Recruit Count
336
Registration Number
NCT04536337
Locations
🇦🇺

Saint Vincent's Hospital Melbourne, Fitzroy, Victoria, Australia

🇬🇧

King's College Hospital, London, United Kingdom

🇨🇳

The Second Affiliated Hospital of Chongqing Medical University, Chongqing, Chongqing, China

and more 9 locations

Stopping Antiviral Treatment in Chronic Hepatitis B

Active, not recruiting
Conditions
Interventions
First Posted Date
2020-06-16
Last Posted Date
2023-05-10
Lead Sponsor
The University of Hong Kong
Target Recruit Count
54
Registration Number
NCT04431245
Locations
🇭🇰

Man Fung Yuen, Hong Kong, Please Select One ..., Hong Kong

A Study of the Oral Farnesoid X Receptor Modulator EYP001a to Assess Its Safety and Anti-viral Effect in Chronic Hepatitis B Patients in Combination With Pegylated Interferon alpha2a Alone and With Entecavir

First Posted Date
2020-04-28
Last Posted Date
2022-08-25
Lead Sponsor
Enyo Pharma
Target Recruit Count
20
Registration Number
NCT04365933
Locations
🇰🇷

ENYO PHARMA Investigative site KR01, Busan, Korea, Republic of

🇨🇳

ENYO PHARMA Investigative site TW03, Kaohsiung, Taiwan

🇨🇳

ENYO PHARMA Investigative site TW04, Kaohsiung, Taiwan

and more 3 locations

Detecting Occult HBV Infection in Liver Donors Positive for Antibody to Hepatitis B Core Antigen (Anti-HBc)

First Posted Date
2019-12-16
Last Posted Date
2022-05-23
Lead Sponsor
The University of Hong Kong
Target Recruit Count
100
Registration Number
NCT04199819
Locations
🇭🇰

The University of Hong Kong, Hong Kong, Hong Kong

Three Types of Nucleotide/Nucleoside Analogues Therapy in Patients With Hepatitis b Virus Related Compensated Cirrhosis

First Posted Date
2019-12-12
Last Posted Date
2019-12-12
Lead Sponsor
Third Affiliated Hospital, Sun Yat-Sen University
Target Recruit Count
150
Registration Number
NCT04196998
Locations
🇨🇳

Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

Three Types of Nucleotide/Nucleoside Analogues Therapy in Patients With Chronic Hepatitis b

First Posted Date
2019-12-11
Last Posted Date
2019-12-17
Lead Sponsor
Third Affiliated Hospital, Sun Yat-Sen University
Target Recruit Count
300
Registration Number
NCT04195074
Locations
🇨🇳

Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

Risk of Hepatocellular Carcinoma in Patients Treated With ETV vs TDF for Chronic Hepatitis B With Compensated Cirrhosis

First Posted Date
2019-11-13
Last Posted Date
2019-11-13
Lead Sponsor
Qing XIe
Target Recruit Count
4000
Registration Number
NCT04160897
Locations
🇨🇳

Rui Jin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, Shanghai, China

RCT of Different Effects of Nucleot(s)Ide Analogues on the Prognosis of HBV-HCC Patients After Curative Resection

Phase 4
Active, not recruiting
Conditions
Interventions
First Posted Date
2019-07-25
Last Posted Date
2022-05-25
Lead Sponsor
West China Hospital
Target Recruit Count
104
Registration Number
NCT04032860
Locations
🇨🇳

West China Hospital, Sichuan University, Chengdu, Sichuan, China

Tenofovir Alafenamide Versus Entecavir for the Treatment of Chronic Hepatitis B

First Posted Date
2019-05-01
Last Posted Date
2023-10-10
Lead Sponsor
Taichung Veterans General Hospital
Target Recruit Count
420
Registration Number
NCT03933384
Locations
🇨🇳

Taichung Veterans General Hospital, Taichung, Taiwan

Three Types of Nucleotide/Nucleoside Analogues Treatment in HBV Related ACLF

First Posted Date
2019-04-19
Last Posted Date
2024-11-28
Lead Sponsor
Third Affiliated Hospital, Sun Yat-Sen University
Target Recruit Count
150
Registration Number
NCT03920618
Locations
🇨🇳

Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

© Copyright 2024. All Rights Reserved by MedPath