MedPath

BMS-986020

Generic Name
BMS-986020
Drug Type
Small Molecule
Chemical Formula
C29H26N2O5
CAS Number
1257213-50-5
Unique Ingredient Identifier
38CTP01B4L
Background

BMS-986020 is under investigation in clinical trial NCT02017730 (To Evaluate The Relationship Between Plasma Drug Levels And Receptor Binding in Lung Using PET (Positron Emission Tomography) In Healthy Volunteers).

Lilly's Olumiant Shows Promise in Preserving Beta Cell Function in Type 1 Diabetes

• Phase 2 BANDIT trial demonstrates Eli Lilly's Olumiant (baricitinib) can slow progression of type 1 diabetes by preserving insulin-producing beta cell function over 48 weeks of treatment. • Patients receiving Olumiant required significantly less insulin therapy and experienced decreased blood glucose fluctuations compared to placebo, potentially reducing treatment burden. • Researchers identify TYK2 inhibition as another promising approach for type 1 diabetes treatment, with an FDA-approved psoriasis drug potentially offering a dual mechanism to protect beta cells and reduce inflammation.
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