MedPath

LM-108

Generic Name
LM-108

LaNova Medicines Initiates Phase 1 Trial of LM-299, Anti-PD-1/VEGF Bispecific Antibody, for Advanced Solid Tumors

• LaNova Medicines has begun a Phase 1 clinical trial in China for LM-299, a bispecific antibody targeting PD-1 and VEGF, in patients with advanced solid tumors. • Preclinical studies of LM-299 demonstrated strong inhibition of tumor growth and a favorable safety profile, supporting its advancement into human trials. • LaNova anticipates submitting an Investigational New Drug (IND) application to the FDA for LM-299 in the United States in the second half of 2024. • The company's recent $42 million Series C1 financing will support the clinical development of LM-299, along with other pipeline candidates like LM-302 and LM-108.
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