ION-994

Novel Therapies and Lifestyle Interventions Show Promise in Hypertension Management

8 months ago

• Recent trials highlight the potential of salt substitution and restriction in lowering blood pressure, particularly in elderly care facilities, showcasing significant cardiovascular benefits. • Emerging drug therapies, including aldosterone synthase inhibitors like baxdrostat and lorundrostat, demonstrate efficacy in treatment-resistant hypertension by targeting aldosterone production. • Bariatric surgery has shown sustained reductions in blood pressure over five years in obese patients with hypertension, suggesting a durable impact on cardiovascular health. • SGLT2 inhibitors, initially for diabetes, are recognized for their beneficial effects on blood pressure regulation, offering a dual-action approach for patients with both conditions.

Novel Therapies and Lifestyle Interventions Show Promise in Hypertension Management

Drug Development Updates