MedPath

Sym-023

Generic Name
Sym-023

Novartis Discontinues Phase 3 Trial of Sabatolimab for Myelodysplastic Syndromes

Novartis has halted the phase 3 STIMULUS-MDS2 trial of sabatolimab, a Tim3-targeting drug, for treating myelodysplastic syndromes (MDS) due to not meeting its primary endpoint. The decision reflects a strategic shift to prioritize other projects within Novartis' portfolio. This development marks a significant setback in the race to bring a Tim3-targeting therapy to market, amidst broader challenges in the field.
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