Mogamulizumab

Generic Name
Mogamulizumab
Brand Names
Poteligeo
Drug Type
Biotech
Chemical Formula
-
CAS Number
1159266-37-1
Unique Ingredient Identifier
YI437801BE
Background

Mogamulizumab is a humanized monoclonal antibody (mAb) directed against CC chemokine receptor 4 (CCR4) for the treatment of Mycosis Fungoides (MF) and Sézary Syndrome (SS), the most common subtypes of cutaneous T-cell lymphoma. Cutaneous T-cell lymphomas occur when certain white blood cells, called T cells, become cancerous; these cancers typically affect th...

Indication

Mogamulizumab is indicated for the treatment of adult patients with relapsed or refractory mycosis fungoides (MF) or Sézary syndrome (SS) after at least one prior systemic therapy.

Associated Conditions
Refractory Mycosis Fungoides and Sezary Syndrome, Relapsed Mycosis Fungoides/Sezary Syndrome
Associated Therapies
-

KHK2455 Alone and in Combination With Mogamulizumab in Subjects With Locally Advanced or Metastatic Solid Tumors

Phase 1
Completed
Conditions
Interventions
First Posted Date
2016-08-15
Last Posted Date
2024-04-25
Lead Sponsor
Kyowa Kirin, Inc.
Target Recruit Count
36
Registration Number
NCT02867007

Study of Mogamulizumab + Docetaxel in Subjects With Non-small Cell Lung Cancer

First Posted Date
2015-02-09
Last Posted Date
2018-11-30
Lead Sponsor
Kyowa Kirin, Inc.
Target Recruit Count
13
Registration Number
NCT02358473
Locations
🇺🇸

Gabrail Cancer Center Research, Canton, Ohio, United States

🇺🇸

John Hopkins University School of Medicine, Baltimore, Maryland, United States

🇺🇸

Horizon Oncology, Lafayette, Indiana, United States

and more 2 locations
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