Imipramine
- Generic Name
- Imipramine
- Brand Names
- Tofranil
- Drug Type
- Small Molecule
- Chemical Formula
- C19H24N2
- CAS Number
- 50-49-7
- Unique Ingredient Identifier
- OGG85SX4E4
- Background
Imipramine, the prototypical tricyclic antidepressant (TCA), is a dibenzazepine-derivative TCA. TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, imipramine does not affect mood or arousal, but may cause sedation. In depressed individuals, i...
- Indication
For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older .
...
- Associated Conditions
- Attention Deficit Hyperactivity Disorder (ADHD), Bulimia Nervosa, Depression, Enuresis, Neuropathic Pain, Panic Disorder
- Associated Therapies
- -
Imipramine and Pregabalin Combination in Painful Polyneuropathy
- Conditions
- Interventions
- First Posted Date
- 2010-01-13
- Last Posted Date
- 2010-01-13
- Lead Sponsor
- Odense University Hospital
- Target Recruit Count
- 75
- Registration Number
- NCT01047488
- Locations
- 🇩🇰
Department of Neurology, Aalborg Hospital, Aalborg, Denmark
🇩🇰Department of Neurology, Odense University Hospital, Odense, Denmark
🇩🇰Department of Neurology, Aarhus University Hospital, Århus, Denmark
Medication Effects on Periurethral Sensation,Urethral Sphincter Activity and Pressure Flow Parameters
- Conditions
- Interventions
- First Posted Date
- 2009-12-09
- Last Posted Date
- 2012-06-08
- Lead Sponsor
- University of Alabama at Birmingham
- Target Recruit Count
- 56
- Registration Number
- NCT01028014
- Locations
- 🇺🇸
University of Alabama at Birmingham, The Kirklin Clinic, Birmingham, Alabama, United States
Dichotic Listening as a Predictor of Medication Response in Depression
- Conditions
- Interventions
- First Posted Date
- 2006-11-29
- Last Posted Date
- 2018-04-30
- Lead Sponsor
- New York State Psychiatric Institute
- Target Recruit Count
- 17
- Registration Number
- NCT00404755
- Locations
- 🇺🇸
New York State Psychiatric Institute, New York, New York, United States
Treatment of Depression Following Multiple Brain Tests
- Conditions
- Interventions
- First Posted Date
- 2006-02-27
- Last Posted Date
- 2012-04-27
- Lead Sponsor
- New York State Psychiatric Institute
- Target Recruit Count
- 28
- Registration Number
- NCT00296777
- Locations
- 🇺🇸
Depression Evaluation Service - New York State Psychiatric Institute, New York, New York, United States
Dichotic Listening as a Predictor of Medication Response in Depression
- Conditions
- Interventions
- First Posted Date
- 2006-02-27
- Last Posted Date
- 2019-05-30
- Lead Sponsor
- New York State Psychiatric Institute
- Target Recruit Count
- 25
- Registration Number
- NCT00296725
- Locations
- 🇺🇸
Depression Evaluation Service, New York State Psychiatric Institute, New York, New York, United States
Comparing Various Treatments for Achieving and Maintaining Remission of Depression
- Conditions
- First Posted Date
- 2005-09-28
- Last Posted Date
- 2013-06-25
- Lead Sponsor
- University of Pittsburgh
- Target Recruit Count
- 200
- Registration Number
- NCT00227955
- Locations
- 🇺🇸
Western Psychiatric Institute and Cinic, Pittsburgh, Pennsylvania, United States
The Effect of Imipramine on Early Information Processing
- First Posted Date
- 2005-09-21
- Last Posted Date
- 2011-09-20
- Lead Sponsor
- Birte Glenthoj
- Target Recruit Count
- 20
- Registration Number
- NCT00206999
- Locations
- 🇩🇰
Center for Neuropsychiatric Schizophrenia Research, University of Copenhagen, Psychiatric Center Glostrup, Glostrup, Denmark
The Efficacy of Imipramine in Treatment of Refractory Functional Dyspepsia
- Conditions
- Interventions
- First Posted Date
- 2005-09-14
- Last Posted Date
- 2016-09-16
- Lead Sponsor
- Chinese University of Hong Kong
- Target Recruit Count
- 107
- Registration Number
- NCT00164775
- Locations
- ðŸ‡ðŸ‡°
Prince of Wales Hospital, Hong Kong, Hong Kong
Treatment of Non-Cardiac Chest Pain With Imipramine or Cognitive-Behavioral Therapy
- Conditions
- Locations
- 🇺🇸
University of Alabama at Birmingham, Birmingham, Alabama, United States
Randomized Study of Cognitive-Behavioral Therapy vs Imipramine and Their Combination for Panic Disorder
- Conditions
- First Posted Date
- 2000-02-25
- Last Posted Date
- 2013-02-21
- Lead Sponsor
- Northwell Health
- Target Recruit Count
- 326
- Registration Number
- NCT00004834
Drug Development Updates
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