Vitamin D3

Generic Name
Vitamin D3
Brand Names
Adrovance, Animi-3 With Vitamin D, Citranatal B-calm Kit, Citranatal Harmony, Fosamax Plus D, Fosavance, Infuvite, Infuvite Pediatric, Mvc-fluoride, Natafort, Pregvit, Vidextra
Drug Type
Small Molecule
Chemical Formula
C27H44O
CAS Number
67-97-0
Unique Ingredient Identifier
1C6V77QF41
Background

Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight . Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalcifero...

Indication

Cholecalciferol use is indicated for the treatment of specific medical conditions like refractory rickets (or vitamin D resistant rickets), hypoparathyroidism, and familial hypophosphatemia .
...

Associated Conditions
Bone Fractures, Calcium and Vitamin D Deficiencies, Deficiency of Vitamin D3, Deficiency, Vitamin A, Deficiency, Vitamin D, Hip Fracture, Hypoparathyroidism, Hypophosphatemia, Familial, Menopause, Osteomalacia, Osteoporosis, Postmenopausal Osteoporosis, Vertebral Fractures, Vitamin D Resistant Rickets, Vitamin Deficiency, Severe Bone Resorption, Spine fracture
Associated Therapies
Calcium supplementation, Nutritional supplementation, Vitamin D Supplementation, Vitamin supplementation
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Immunotec® Unveils SunRay: A Breakthrough Once-Weekly Vitamin D Supplement

Immunotec® launches SunRay, a weekly Vitamin D supplement with Calcifediol for rapid absorption and superior health benefits, now available in the U.S. without a prescription.

Vitamin D for the management of chronic obstructive pulmonary disease

Vitamin D supplementation shows little to no effect on COPD exacerbation rates, lung function, adverse events, mortality, or quality of life, according to a meta-analysis of 10 double-blind, randomized, placebo-controlled trials involving 1372 adults with COPD.
globenewswire.com
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SmartyPants Vitamins Launches Science-Backed Immunity Gummy Supplement For Kids

SmartyPants Vitamins launches Kids Triple Action Immunity gummies, containing 67% more nutrients than leading kids immunity gummies, with Vitamin C, D, and Zinc, plus ElderCraft® for antioxidant support. The product is a Clean Label Project® Purity Award Winner, free from major allergens, GMOs, gluten, synthetic colors, and certified vegetarian.

High-dose vitamin D can help delay progression to MS

High-dose cholecalciferol (vitamin D) nearly doubles time for CIS patients to experience new MS activity, significantly reducing disease activity by 34% and new/enlarging lesions, according to D-Lay-MS study. Safe and well-tolerated, it shows potential as add-on therapy for early MS.

Rapid normalization of vitamin D deficiency in PICU (VITdALIZE-KIDS)

VITdALIZE-KIDS is a phase III, multicenter, double-blind RCT designed with CCCTG to assess vitamin D supplementation in PICU patients. The trial will recruit 766 patients from 11 Canadian centers, with randomization stratified by site. The primary outcome is HRQL at 28 ± 7 days post-intervention, measured by PedsQL™. A metabolomics sub-study will analyze blood and urine samples to understand the broader metabolic effects of vitamin D correction. Safety monitoring includes reporting adverse events and following Health Canada guidelines. The trial protocol adheres to SPIRIT guidelines and has received necessary ethical and regulatory approvals.
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