Vitamin D3

Generic Name: Vitamin D3

Brand Names: Adrovance, Animi-3 With Vitamin D, Citranatal B-calm Kit, Citranatal Harmony, Fosamax Plus D, Fosavance, Infuvite, Infuvite Pediatric, Mvc-fluoride, Natafort, Pregvit, Vidextra

Drug Type: Small Molecule

Chemical Formula: C_₂₇H_₄₄O

CAS Number: 67-97-0

Unique Ingredient Identifier: 1C6V77QF41

Background: Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight . Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalcifero...

Indication: Cholecalciferol use is indicated for the treatment of specific medical conditions like refractory rickets (or vitamin D resistant rickets), hypoparathyroidism, and familial hypophosphatemia .
...

Associated Conditions: Bone Fractures, Calcium and Vitamin D Deficiencies, Deficiency of Vitamin D3, Deficiency, Vitamin A, Deficiency, Vitamin D, Hip Fracture, Hypoparathyroidism, Hypophosphatemia, Familial, Menopause, Osteomalacia, Osteoporosis, Postmenopausal Osteoporosis, Vertebral Fractures, Vitamin D Resistant Rickets, Vitamin Deficiency, Severe Bone Resorption, Spine fracture

Associated Therapies: Calcium supplementation, Nutritional supplementation, Vitamin D Supplementation, Vitamin supplementation

Clinical Trials

Cholecalciferol Versus Doxercalciferol in the Treatment of Secondary Hyperparathyroidism in Chronic Kidney Disease

Not Applicable

Completed

Conditions: Renal Osteodystrophy

Interventions: Drug: doxercalciferol
Drug: Cholecalciferol

First Posted Date: 2006-02-02

Last Posted Date: 2016-05-02

Lead Sponsor: Indiana University School of Medicine

Target Recruit Count: 55

Registration Number: NCT00285467

Locations: 🇺🇸
Indiana University School of Medicine, Indianapolis, Indiana, United States

High Dose Vit D Musculoskeletal Symptoms & Bone Density in Anastrozole-Treated Breast Cancer With Marginal Vit D Status

Early Phase 1

Completed

Conditions: Breast Neoplasms

Interventions: Dietary Supplement: Calcium carbonate
Other: Placebo
Drug: Vitamin D

First Posted Date: 2005-12-07

Last Posted Date: 2014-09-22

Lead Sponsor: Washington University School of Medicine

Target Recruit Count: 63

Registration Number: NCT00263185

Locations: 🇺🇸
Washington University, St. Louis, Missouri, United States

Treatment of Obesity With Vitamin D (40.000 IE Per Week for 1 Year)

Phase 2

Completed

Conditions: Obesity

First Posted Date: 2005-10-21

Last Posted Date: 2008-05-14

Lead Sponsor: University of Tromso

Target Recruit Count: 450

Registration Number: NCT00243256

Locations: 🇳🇴
Clinical Research Unit, University Hospital of North Norway, Tromsø, Norway

Vitamin D Administration in the Nursing Home

Not Applicable

Completed

Conditions: Osteoporosis
Vitamin D Deficiency

Interventions: Drug: placebo
Drug: Vitamin D

First Posted Date: 2005-09-20

Last Posted Date: 2023-10-04

Lead Sponsor: University of Wisconsin, Madison

Target Recruit Count: 96

Registration Number: NCT00204919

Locations: 🇺🇸
University of Wisconsin, Madison, Wisconsin, United States

Vitamin D/Calcium Polyp Prevention Study

Phase 2

Completed

Conditions: Polyps
Adenomas
Colorectal Cancer

Interventions: Drug: placebo
Drug: Calcium Carbonate
Drug: Vitamin D3

First Posted Date: 2005-09-12

Last Posted Date: 2017-03-15

Lead Sponsor: Dartmouth-Hitchcock Medical Center

Target Recruit Count: 2813

Registration Number: NCT00153816

Locations: 🇺🇸
University of North Carolina, Chapel Hill, North Carolina, United States
🇺🇸
University of Southern California, Los Angeles, California, United States
🇺🇸
University of Colorado, Denver, Colorado, United States

and more 8 locations

ACHIEVE: Optimizing the Treatment of Secondary Hyperparathyroidism

Phase 4

Completed

Conditions: Secondary Hyperparathyroidism

Interventions: Drug: Sensipar®
Drug: Vitamin D

First Posted Date: 2005-08-26

Last Posted Date: 2014-02-11

Lead Sponsor: Amgen

Target Recruit Count: 170

Registration Number: NCT00135304

Early Rehabilitation After Hip Fracture

Phase 3

Conditions: Accidental Falls
Fractures
Hip Fractures

First Posted Date: 2005-08-23

Last Posted Date: 2006-09-11

Lead Sponsor: Swiss National Science Foundation

Target Recruit Count: 204

Registration Number: NCT00133640

Locations: 🇨🇭
Triemli Hospital, Zurich, Switzerland

Vitamin D Treatment for Crohn´s Disease

Phase 2

Conditions: Crohns Disease

First Posted Date: 2005-08-19

Last Posted Date: 2007-04-13

Lead Sponsor: University of Aarhus

Target Recruit Count: 110

Registration Number: NCT00132184

Locations: 🇩🇰
Aarhus University Hospital, Department V, Aarhus, Denmark
🇩🇰
Hospital of Horsens, Horsens, Denmark
🇩🇰
Hospital of Randers, Randers, Denmark

and more 1 locations

The Effect of Alendronate, Calcium, and Vitamin D on Bone Mineral Density in HIV Infected Patients

Phase 2

Completed

Conditions: HIV Infections

First Posted Date: 2003-05-23

Last Posted Date: 2009-08-07

Lead Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Target Recruit Count: 80

Registration Number: NCT00061256

Locations: 🇺🇸
Stanford Univ, Stanford, California, United States
🇺🇸
Chelsea Clinic, New York, New York, United States
🇺🇸
Univ of Minnesota, Minneapolis, Minnesota, United States

and more 25 locations

Vitamin D Metabolism and the Williams Syndrome

Completed

Conditions: Williams Syndrome

First Posted Date: 2001-04-05

Last Posted Date: 2005-06-24

Lead Sponsor: National Center for Research Resources (NCRR)

Registration Number: NCT00013962

Locations: 🇺🇸
Medical University of South Carolina, Charleston, South Carolina, United States

Drug Development Updates

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