Somatotropin
- Generic Name
- Somatotropin
- Brand Names
- Genotropin, Humatrope, Norditropin, Norditropin Nordiflex, Nutropin, Nutropinaq, Omnitrope, Saizen, Serostim, Zomacton, Zorbtive, NutropinAq
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 12629-01-5
- Unique Ingredient Identifier
- NQX9KB6PCL
- Background
Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood glucose level regulation, and li...
- Indication
Somatotropin is indicated for the treatment of pediatric patients who have growth failure due to an inadequate secretion of endogenous growth hormone, short stature associated with Turner syndrome, Prader-Willi syndrome (PWS), idiopathic short stature (ISS), short stature or growth failure in short stature homeobox-containing gene (SHOX) deficiency, and shor...
- Associated Conditions
- Adult Onset Growth Hormone Deficiency, Cachexia, Childhood-onset Growth Hormone Deficiency, Growth Failure, HIV Wasting Syndrome, Short Bowel Syndrome (SBS), Short Stature
- Associated Therapies
- -
Evolution Of Growth Rate In Children With Growth Retardation Due to Glucocorticosteroid Therapy And Treated By Genotonorm
- First Posted Date
- 2005-09-13
- Last Posted Date
- 2024-02-21
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 98
- Registration Number
- NCT00163189
- Locations
- 🇫🇷
Centre de Perharidy, Roscoff Cedex, France
🇫🇷Hôpital Lenval, Nice, France
🇫🇷CHU Timone Enfants, Marseille Cedex 5, France
Growth Hormone Administration and Its Effects on Cardiovascular Risk Factors in Growth Hormone Deficient Women
- Conditions
- Interventions
- First Posted Date
- 2005-08-26
- Last Posted Date
- 2008-02-18
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 63
- Registration Number
- NCT00136032
- Locations
- 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
Arimidex Multicenter Trial in Growth Hormone (GH) Deficient Boys
- Conditions
- Interventions
- First Posted Date
- 2005-08-23
- Last Posted Date
- 2011-10-12
- Lead Sponsor
- Nemours Children's Clinic
- Target Recruit Count
- 53
- Registration Number
- NCT00133354
- Locations
- 🇺🇸
Nemours Children's Clinic, Jacksonville, Florida, United States
Trial of Growth Hormone Therapy in Pediatric Crohn's Disease
- First Posted Date
- 2005-04-29
- Last Posted Date
- 2020-10-30
- Lead Sponsor
- Children's Hospital Medical Center, Cincinnati
- Target Recruit Count
- 22
- Registration Number
- NCT00109473
- Locations
- 🇺🇸
Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States
Somatropin (Norditropin) in Insulin-like Growth Factor (IGF) Deficient Children
- Conditions
- First Posted Date
- 2005-02-02
- Last Posted Date
- 2017-01-18
- Lead Sponsor
- Novo Nordisk A/S
- Target Recruit Count
- 149
- Registration Number
- NCT00102817
- Locations
- 🇺🇸
Novo Nordisk Investigational Site, Milwaukee, Wisconsin, United States
Physiologic Growth Hormone Effects in HIV Lipodystrophy
- Conditions
- Interventions
- First Posted Date
- 2005-01-05
- Last Posted Date
- 2010-07-27
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 56
- Registration Number
- NCT00100698
- Locations
- 🇺🇸
MGH, Boston, Massachusetts, United States
Diet/Growth Factor Mechanisms of Gut Adaptation
- Conditions
- First Posted Date
- 2003-09-01
- Last Posted Date
- 2016-05-16
- Lead Sponsor
- Emory University
- Target Recruit Count
- 27
- Registration Number
- NCT00067860
- Locations
- 🇺🇸
Emory University School of Medicine, Atlanta, Georgia, United States
Administration of Growth Hormone to Increase CD4+ Count in Patients Taking Anti-HIV Drugs
- Conditions
- First Posted Date
- 2003-01-01
- Last Posted Date
- 2021-11-01
- Target Recruit Count
- 60
- Registration Number
- NCT00050921
- Locations
- 🇺🇸
Alabama Therapeutics CRS, Birmingham, Alabama, United States
🇺🇸UCLA CARE Center CRS, Los Angeles, California, United States
🇺🇸UC Davis Medical Center, Sacramento, California, United States
Growth Hormone Treatment of Children With HIV-Associated Growth Failure
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2021-11-01
- Target Recruit Count
- 102
- Registration Number
- NCT00006143
- Locations
- 🇺🇸
Childrens Hosp. LA - Dept. of Ped., Div. of Clinical Immunology & Allergy, Los Angeles, California, United States
🇺🇸South Florida CDC Ft Lauderdale NICHD CRS, Fort Lauderdale, Florida, United States
🇺🇸Emory Univ. School of Medicine, Dept. of Peds., Div. of Infectious Diseases, Atlanta, Georgia, United States
Phase II Study of Growth Hormone in Children With Cystic Fibrosis
- Conditions
- First Posted Date
- 2001-05-07
- Last Posted Date
- 2008-09-09
- Lead Sponsor
- University of Utah
- Target Recruit Count
- 40
- Registration Number
- NCT00016445
- Locations
- 🇺🇸
T.L. Carey, M.D. and Associates, Tulsa, Oklahoma, United States
🇺🇸Washington University, Saint Louis, Missouri, United States
🇺🇸Children's Medical Center - Dayton, Dayton, Ohio, United States
Drug Development Updates
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