Tyramine

Generic Name: Tyramine

Brand Names: -

Drug Type: Small Molecule

Chemical Formula: C_₈H_₁₁NO

CAS Number: 51-67-2

Unique Ingredient Identifier: X8ZC7V0OX3

Background: Tyramine (4-hydroxyphenethylamine; para-tyramine, mydrial or uteramin) is a naturally occurring monoamine compound and trace amine derived from the amino acid tyrosine. Tyramine acts by inducing the release of catecholamine. An important characteristic of this product is its impediment to cross the blood-brain barrier which restrains its side effects to only...

Associated Conditions: -

Associated Therapies: -

Clinical Trials

A Study in Healthy People to Test How Combining BI 1467335 and Tyramine Affects Blood Pressure

Phase 1

Terminated

Conditions: Healthy

Interventions: Drug: BI 1467335
Drug: Phenelzine sulfate
Drug: Placebo
Drug: Tyramine

First Posted Date: 2019-06-07

Last Posted Date: 2021-06-04

Lead Sponsor: Boehringer Ingelheim

Target Recruit Count: 53

Registration Number: NCT03979820

Locations: 🇳🇱
PRA Health Sciences Onderzoekscentrum Martini, Groningen, Netherlands

Drug-drug Interaction Study of Ozanimod With Tyramine to Evaluate the Effect on Pressor Response

Phase 1

Completed

Conditions: Healthy Volunteer

Interventions: Drug: Phenelzine
Drug: Tyramine
Drug: Phenelzine placebo
Drug: ozanimod
Drug: ozanimod placebo

First Posted Date: 2018-10-03

Last Posted Date: 2019-07-19

Lead Sponsor: Celgene

Target Recruit Count: 92

Registration Number: NCT03694119

Locations: 🇺🇸
PPD Phase 1 Clinic, Austin, Texas, United States

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