Flumazenil
- Generic Name
- Flumazenil
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C15H14FN3O3
- CAS Number
- 78755-81-4
- Unique Ingredient Identifier
- 40P7XK9392
- Background
Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine receptor complex, thereby reversing the effects of benzodiazepine on the central nervous system.
- Indication
For the complete or partial reversal of the sedative effects of benzodiazepines in cases where general anesthesia has been induced and/or maintained with benzodiazepines, and where sedation has been produced with benzodiazepines for diagnostic and therapeutic procedures. Also for the management of benzodiazepine overdose as an adjunct for appropriate supportive and symptomatic measures.
- Associated Conditions
- Sedation caused by benzodiazepine
- Associated Therapies
- Anesthesia, Reversal, Reversal of sedation therapy
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