MedPath

Acyclovir

Generic Name
Acyclovir
Brand Names
Sitavig, Xerese, Zovirax
Drug Type
Small Molecule
Chemical Formula
C8H11N5O3
CAS Number
59277-89-3
Unique Ingredient Identifier
X4HES1O11F

Overview

Acyclovir is a nucleotide analog antiviral used to treat herpes simplex, Varicella zoster, herpes zoster, herpes labialis, and acute herpetic keratitis. Acyclovir is generally used first line in the treatment of these viruses and some products are indicated for patients as young as 6 years old. Acyclovir was granted FDA approval on 29 March 1982.

Background

Acyclovir is a nucleotide analog antiviral used to treat herpes simplex, Varicella zoster, herpes zoster, herpes labialis, and acute herpetic keratitis. Acyclovir is generally used first line in the treatment of these viruses and some products are indicated for patients as young as 6 years old. Acyclovir was granted FDA approval on 29 March 1982.

Indication

An acyclovir topical cream is indicated to treat recurrent herpes labialis in immunocompetent patients 12 years and older. Acyclovir oral tablets, capsules, and suspensions are indicated to treat herpes zoster, genital herpes, and chickenpox. An acyclovir topical ointment is indicated to treat initial genital herpes and limited non-life-threatening mucocutaneous herpes simplex in immunocompromised patients. An acyclovir cream with hydrocortisone is indicated to treat recurrent herpes labialis, and shortening lesion healing time in patients 6 years and older. An acyclovir buccal tablet is indicated for the treatment of recurrent herpes labialis. An acyclovir ophthalmic ointment is indicated to treat acute herpetic keratitis.

Associated Conditions

  • Bell's Palsy
  • Chickenpox
  • Cytomegalovirus (CMV) Infections
  • Herpes Simplex Infections
  • Herpes Zoster
  • Herpes simplex encephalitis
  • Herpes simplex of the oral-labial
  • Herpes simplex type I reactivation
  • Recurrent Genital Herpes (RGH)
  • Recurrent Herpes Labialis
  • VZV re-activation
  • Acute Genital herpes
  • Acute Herpes labialis
  • Acute Herpetic keratitis
  • Severe Genital herpes

FDA Approved Products

acyclovir
Manufacturer:Zydus Pharmaceuticals (USA) Inc.
Route:ORAL
Strength:400 mg in 1 1
Approved: 2023/10/24
NDC:68382-791
acyclovir
Manufacturer:Zydus Pharmaceuticals (USA) Inc.
Route:ORAL
Strength:800 mg in 1 1
Approved: 2023/10/24
NDC:68382-792
ACYCLOVIR
Manufacturer:AvKARE
Route:ORAL
Strength:200 mg in 1 1
Approved: 2024/01/09
NDC:42291-017
Acyclovir
Manufacturer:Quality Care Products, LLC
Route:ORAL
Strength:800 mg in 1 1
Approved: 2020/01/30
NDC:55700-835
Acyclovir
Manufacturer:American Health Packaging
Route:ORAL
Strength:800 mg in 1 1
Approved: 2022/10/04
NDC:68084-109

Singapore Approved Products

No Singapore products found for this drug

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