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Hydroxyethyl Starch

Generic Name
Hydroxyethyl Starch
Brand Names
Hespan, Hextend, Volulyte, Voluven
Drug Type
Small Molecule
CAS Number
9005-27-0
Unique Ingredient Identifier
875Y4127EA

Overview

Hydroxyethyl starch (HES/HAES) is a nonionic starch derivative. Hydroxyethyl starches (HES) are synthetic colloids commonly used for fluid resuscitation to replace intravascular volume. HES is a general term and can be sub-classified according to average molecular weight, molar substitution, concentration, C2/C6 ratio and Maximum Daily Dose.

Background

Hydroxyethyl starch (HES/HAES) is a nonionic starch derivative. Hydroxyethyl starches (HES) are synthetic colloids commonly used for fluid resuscitation to replace intravascular volume. HES is a general term and can be sub-classified according to average molecular weight, molar substitution, concentration, C2/C6 ratio and Maximum Daily Dose.

Indication

An intravenous solution of hydroxyethyl starch is used to prevent shock following severe blood loss caused by trauma, surgery, or other issues.

Associated Conditions

  • Hypovolaemia

Clinical Trials

Not Applicable
Recruiting
Posted: 2022/07/27
Sponsor:
General Hospital of ...
Completed
Posted: 2020/09/28
Sponsor:
The George Institute...
Not Applicable
Completed
Posted: 2018/09/19
Sponsor:
Holbaek Sygehus

FDA Approved Products

Hetastarch in Sodium Chloride
Manufacturer:Hospira, Inc.
Route:INTRAVENOUS
Strength:6 g in 100 mL
Approved: 2022/07/21
NDC:0409-7248
6% HETASTARCH IN 0.9% SODIUM CHLORIDE
Manufacturer:HF Acquisition Co LLC, DBA HealthFirst
Route:INTRAVENOUS
Strength:6 g in 100 mL
Approved: 2024/01/29
NDC:51662-1317
Hextend
Manufacturer:Hospira, Inc.
Route:INTRAVENOUS
Strength:6 g in 100 mL
Approved: 2023/02/15
NDC:0409-1555

Singapore Approved Products

VOLUVEN SOLUTION FOR INFUSION 6%
Manufacturer:FRESENIUS KABI DEUTSCHLAND GMBH
Form:INJECTION
Strength:60 g/l
Online:Yes
Approved: 2003/05/16
Approval:SIN12297P

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