MedPath

Tenofovir

Generic Name
Tenofovir
Brand Names
Vemlidy, Tenofovir disoproxil Zentiva
Drug Type
Small Molecule
Chemical Formula
C9H14N5O4P
CAS Number
147127-20-6
Unique Ingredient Identifier
W4HFE001U5

Overview

Tenofovir is an acyclic nucleotide diester analog of adenosine monophosphate. In the most strict sense and due to the fact that it presents a phosphate group bound to the nitrogenous base, it is determined as an actual nucleotide analog. The antiviral activities of tenofovir were first reported in 1993 and this agent was commercially available since 2008 in the form of tenofovir disoproxil and tenofovir alafenamide in order to obtain oral bioavailability.

Background

Tenofovir is an acyclic nucleotide diester analog of adenosine monophosphate. In the most strict sense and due to the fact that it presents a phosphate group bound to the nitrogenous base, it is determined as an actual nucleotide analog. The antiviral activities of tenofovir were first reported in 1993 and this agent was commercially available since 2008 in the form of tenofovir disoproxil and tenofovir alafenamide in order to obtain oral bioavailability.

Indication

Tenofovir has been shown to be effective against HIV, herpes simplex virus-2, and hepatitis B virus. To know more about the specific product indications, please visit the information in the orally available forms of tenofovir, tenofovir alafenamide and tenofovir disoproxil.

Associated Conditions

No associated conditions information available.

FDA Approved Products

DESCOVY
Manufacturer:Gilead Sciences, Inc.
Route:ORAL
Strength:15 mg in 1 1
Approved: 2022/01/20
NDC:61958-2005
ODEFSEY
Manufacturer:A-S Medication Solutions
Route:ORAL
Strength:25 mg in 1 1
Approved: 2017/08/28
NDC:50090-2340
Biktarvy
Manufacturer:Gilead Sciences, Inc.
Route:ORAL
Strength:25 mg in 1 1
Approved: 2024/02/28
NDC:61958-2501
ODEFSEY
Manufacturer:Gilead Sciences, Inc.
Route:ORAL
Strength:25 mg in 1 1
Approved: 2021/09/17
NDC:61958-2101
Biktarvy
Manufacturer:Gilead Sciences, Inc.
Route:ORAL
Strength:15 mg in 1 1
Approved: 2024/02/28
NDC:61958-2505

Singapore Approved Products

No Singapore products found for this drug

Drug Development Updates

Stay informed with timely notifications on clinical trials and research advancements.

© Copyright 2025. All Rights Reserved by MedPath