Diethylcarbamazine
- Generic Name
- Diethylcarbamazine
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C10H21N3O
- CAS Number
- 90-89-1
- Unique Ingredient Identifier
- V867Q8X3ZD
- Background
An anthelmintic used primarily as the citrate in the treatment of filariasis, particularly infestations with Wucheria bancrofti or Loa loa.
- Indication
Used for the treatment of certain filarial diseases, including tropical pulmonary eosinophilia, loiasis, and lymphatic filariasis caused by infection with Wuchereria bancrofti, Brugia malayi, or Brugia timori.
- Associated Conditions
- Filarial Infection, Onchocerciasis
- Associated Therapies
- -
Moxidectin for LF, Cote d'Ivoire (DOLF)
- Conditions
- Interventions
- First Posted Date
- 2020-06-01
- Last Posted Date
- 2023-10-27
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 164
- Registration Number
- NCT04410406
- Locations
- 🇨🇮
Regional Hospital of Agboville, Southern Cote d'Ivoire, Agboville, Côte D'Ivoire
PK PD Study of IDA and Azithromycin for NTDs ( ComboNTDs )
- Conditions
- Interventions
- First Posted Date
- 2018-09-10
- Last Posted Date
- 2019-02-28
- Lead Sponsor
- Lihir Medical Centre
- Target Recruit Count
- 42
- Registration Number
- NCT03664063
- Locations
- 🇵🇬
Lihir Medical Centre, Londolovit, New Ireland Province, Papua New Guinea
Lymphatic Filariasis (LF) in Ivory Coast
- Conditions
- Interventions
- First Posted Date
- 2016-11-28
- Last Posted Date
- 2022-04-21
- Lead Sponsor
- University Hospitals Cleveland Medical Center
- Target Recruit Count
- 189
- Registration Number
- NCT02974049
- Locations
- 🇨🇮
Cote d'Ivoire, Abidjan, Côte D'Ivoire
Alternate Chemotherapy Regimens for the Clearance of W.Bancrofti Infection
- Conditions
- Interventions
- First Posted Date
- 2013-12-09
- Last Posted Date
- 2013-12-09
- Lead Sponsor
- Indian Council of Medical Research
- Target Recruit Count
- 146
- Registration Number
- NCT02005653
- Locations
- 🇮🇳
Vector Control Research Centre, Pondicherry, India
Eval 3-Drug Therapy Diethylcarbamize, Albendazole and Ivermectin That Could Accelerate LF Elimination Outside of Africa
- Conditions
- Interventions
- First Posted Date
- 2013-11-03
- Last Posted Date
- 2018-10-09
- Lead Sponsor
- University Hospitals Cleveland Medical Center
- Target Recruit Count
- 182
- Registration Number
- NCT01975441
- Locations
- 🇵🇬
Papua New Guinean Institute for Medical Research, Maprik, East Sepik, Papua New Guinea
Post-treatment Effects of Ivermectin (IVM) or Diethylcarbamazine (DEC) in Loiasis
- First Posted Date
- 2012-05-08
- Last Posted Date
- 2016-11-09
- Target Recruit Count
- 155
- Registration Number
- NCT01593722
- Locations
- 🇨🇲
Filariasis and other Tropical Diseases Research Center, Yaounde, Cameroon
Reslizumab to Prevent Post-treatment Eosinophilia in Loiasis
- Conditions
- Interventions
- First Posted Date
- 2010-04-27
- Last Posted Date
- 2022-01-27
- Target Recruit Count
- 31
- Registration Number
- NCT01111305
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
Effect of Albendazole Dose on Treatment of Lymphatic Filariasis
- Conditions
- Interventions
- First Posted Date
- 2007-08-03
- Last Posted Date
- 2015-08-31
- Target Recruit Count
- 40
- Registration Number
- NCT00511004
- Locations
- 🇮🇳
Filariasis Chemotherapy Unit (FCU), T.D. Medical Hospital, Alleppey, Kerala, India
Interaction Between HIV and Lymphatic Filariasis
- Conditions
Host Response to Infection and Treatment in Filarial Diseases
- Conditions
- Interventions
- First Posted Date
- 1999-11-04
- Last Posted Date
- 2024-11-19
- Target Recruit Count
- 500
- Registration Number
- NCT00001230
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
Drug Development Updates
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