Overview
Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. In particular, the RRR-alpha-tocopherol (or sometimes called the d-alpha-tocopherol stereoisomer) stereoisomer is considered the natural formation of alpha-tocopherol and generally exhibits the greatest bioavailability out of all of the alpha-tocopherol stereoisomers. Moreover, RRR-alpha-tocopherol acetate is a relatively stabilized form of vitamin E that is most commonly used as a food additive when needed . Alpha-tocopherol acetate is subsequently most commonly indicated for dietary supplementation in individuals who may demonstrate a genuine deficiency in vitamin E. Vitamin E itself is naturally found in various foods, added to others, or used in commercially available products as a dietary supplement. The recommended dietary allowances (RDAs) for vitamin E alpha-tocopherol are: males = 4 mg (6 IU) females = 4 mg (6 IU) in ages 0-6 months, males = 5 mg (7.5 IU) females = 5 mg (7.5 IU) in ages 7-12 months, males = 6 mg (9 IU) females = 6 mg (9 IU) in ages 1-3 years, males = 7 mg (10.4 IU) females = 7 mg (10.4 IU) in ages 4-8 years, males = 11 mg (16.4 IU) females = 11 mg (16.4 IU) in ages 9-13 years, males = 15 mg (22.4 IU) females = 15 mg (22.4 IU) pregnancy = 15 mg (22.4 IU) lactation = 19 mg (28.4 IU) in ages 14+ years . Most individuals obtain adequate vitamin E intake from their diets; genuine vitamin E deficiency is considered to be rare. Nevertheless, vitamin E is known to be a fat-soluble antioxidant that has the capability to neutralize endogenous free radicals. This biologic action of vitamin E consequently continues to generate ongoing interest and study in whether or not its antioxidant abilities may be used to help assist in preventing or treating a number of different conditions like cardiovascular disease, ocular conditions, diabetes, cancer and more. At the moment however, there exists a lack of formal data and evidence to support any such additional indications for vitamin E use.
Indication
In addition to any following information, owing to d-alpha-Tocopherol acetate's closely related chemical nature with alpha-Tocopherol acetate, please also refer to the drug information page for alpha-Tocopherol acetate for further data. Vitamin E, known for its antioxidant activities, is protective against cardiovascular disease and some forms of cancer and has also demonstrated immune-enhancing effects. It may be of limited benefit in some with asthma and rheumatoid arthritis. It may be helpful in some neurological diseases including Alzheimer's, some eye disorders including cataracts, and diabetes and premenstrual syndrome. It may also help protect skin from ultraviolet irradiation although claims that it reverses skin aging, enhances male fertility and exercise performance are poorly supported. It may help relieve some muscle cramps.
Associated Conditions
No associated conditions information available.
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
---|
No clinical trials found
No clinical trials found for this drug
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
---|---|---|---|---|---|
No FDA approvals found for this drug. |
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
---|---|---|---|
No EMA approvals found for this drug. |
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
---|---|---|---|---|---|
No HSA approvals found for this drug. |
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
---|---|---|---|---|---|
No NMPA approvals found for this drug. |
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
---|---|---|---|---|---|
No PPB approvals found for this drug. |
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
---|---|---|---|---|---|
S.O.H Superior Omega 3 High Potency | 280858 | Medicine | A | 9/29/2016 | |
Kids Multi | 329564 | Medicine | A | 2/6/2020 | |
PREMEO | 172667 | Medicine | A | 6/29/2010 | |
Bio Solution DHA Growth | 323160 | Medicine | A | 9/13/2019 | |
BLACKMORES ULTIMATE RADIANT SKIN | 364753 | Medicine | A | 5/6/2021 | |
Nature's Family Premium Vitamax | 314002 | Nature's Family Australia Pty Ltd | Medicine | A | 2/7/2019 |
UltraClean EPA/DHA Plus | 309331 | Medicine | A | 9/17/2018 | |
InNatal | 346421 | Medicine | A | 10/22/2020 | |
Chemists' Own PROVANCE Clean EPA/DHA | 370293 | Medicine | A | 6/28/2021 | |
GO Royal Jelly + Vitamin E | 445391 | Medicine | A | 4/5/2024 |
Health Canada Drug Approvals
Approved Product | Company | DIN | Dosage Form | Strength | Market Date |
---|---|---|---|---|---|
C.E.B12 COMPLEX PWR | pure life international prods inc. | 02051117 | Powder - Oral | 6 UNIT / G | 12/31/1993 |
VITAMINS E, C & BETA CAROTENE WITH SELENIUM | hillestad pharmaceuticals usa | 02202034 | Wafer - Oral | 180 MG / UNIT | 11/1/1995 |
GRAND MASTER FORMULA TAB | nutrition for life international | 02053349 | Tablet - Oral | 66.67 UNIT | 12/30/1996 |
EFAMOL CALCIUM - CAP | efamol research inc. | 02163993 | Capsule - Oral | 13.6 UNIT | 7/30/1996 |
IRON, VIT & MIN SUPP | avacare, division of jeunique international inc. | 00631426 | Tablet - Oral | 10 UNIT / TAB | 12/31/1985 |
VITAMIN E CAP 200UNIT | shoppers drug mart inc. | 00414956 | Capsule - Oral | 200 UNIT / CAP | 12/31/1977 |
NUTROL V CAPSULE | rolmex international inc. | 02025663 | Capsule - Oral | 50 UNIT | 12/31/1994 |
VITAMIN E 400I.U.WITH SELENIUM 50MCG-TAB | health-wise nutrition inc. | 02167999 | Tablet - Oral | 400 UNIT | 8/15/1997 |
ONE A DAY ADVANCE - ADULTS 50 + - TABS | bayer inc consumer care | 02155206 | Tablet - Oral | 60 UNIT | 12/31/1996 |
PRIMANOL-BORAGE W.BETA-CAR.AND VIT.C AND E | jamieson laboratories ltd | 02050498 | Tablet - Oral | 15 UNIT / TAB | 12/31/1993 |
CIMA AEMPS Drug Approvals
Approved Product | Company | Registration Number | Pharmaceutical Form | Prescription Type | Status |
---|---|---|---|---|---|
No CIMA AEMPS (Spain) approvals found for this drug. |
Philippines FDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
---|---|---|---|---|---|
No Philippines FDA approvals found for this drug. |
Saudi SFDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
---|---|---|---|---|---|
No Saudi SFDA approvals found for this drug. |
Malaysia NPRA Drug Approvals
Approved Product | Company | Registration Number | Dosage Form | Strength | Approval Date |
---|---|---|---|---|---|
No Malaysia NPRA approvals found for this drug. |
UK EMC Drug Information
Medicine Name | MA Holder | MA Number | Pharmaceutical Form | Active Ingredient | Authorization Date |
---|---|---|---|---|---|
No UK EMC drug information found for this drug. |
Help Us Improve
Your feedback helps us provide better drug information and insights.