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Acetohydroxamic acid

Generic Name
Acetohydroxamic acid
Brand Names
Lithostat
Drug Type
Small Molecule
Chemical Formula
C2H5NO2
CAS Number
546-88-3
Unique Ingredient Identifier
4RZ82L2GY5

Overview

Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea. In the urine, it acts as an antagonist of the bacterial enzyme urease. Acetohydroxamic Acid has no direct antimicrobial action and does not acidify urine directly. It is used, in addition to antibiotics or medical procedures, to treat chronic urea-splitting urinary infections.

Background

Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea. In the urine, it acts as an antagonist of the bacterial enzyme urease. Acetohydroxamic Acid has no direct antimicrobial action and does not acidify urine directly. It is used, in addition to antibiotics or medical procedures, to treat chronic urea-splitting urinary infections.

Indication

Used, in addition to antibiotics or medical procedures, to treat chronic urea-splitting urinary infections.

Associated Conditions

  • Chronic urea-splitting urinary infection

Clinical Trials

Phase 1
Terminated
Posted: 2017/06/09
Sponsor:
Nicholas Ah Mew

FDA Approved Products

Lithostat
Manufacturer:Mission Pharmacal Company
Route:ORAL
Strength:250 mg in 1 1
Approved: 2024/01/08
NDC:0178-0500

Singapore Approved Products

No Singapore products found for this drug

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