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Sodium acetate

Generic Name
Sodium acetate
Brand Names
Bss, Bss Ophthalmic Solution, Citrasate, Clinimix E 2.75/5, Hemosate Ultra, Hyperlyte, Intersol, Isolyte P, Isolyte S, Isolyte S pH 7.4, Isoplate, Normosol-R, Olimel, Periolimel, Physiolyte, Physiosol, Plasma-lyte, Plasma-lyte 148, Plasma-lyte 148 In 5 % Dextrose, Plasma-lyte R, Plasmalyte A, Procalamine 3
Drug Type
Small Molecule
Chemical Formula
C2H3NaO2
CAS Number
127-09-3
Unique Ingredient Identifier
NVG71ZZ7P0

Overview

Sodium Acetate is chemically designated CH3COONa, a hygroscopic powder very soluble in water. Sodium acetate could be used as additives in food, industry, concrete manufacture, heating pads and in buffer solutions. Medically, sodium acetate is important component as an electrolyte replenisher when given intravenously. It is mainly indicated to correct sodium levels in hyponatremic patients. It can be used also in metabolic acidosis and for urine alkalinization.

Background

Sodium Acetate is chemically designated CH3COONa, a hygroscopic powder very soluble in water. Sodium acetate could be used as additives in food, industry, concrete manufacture, heating pads and in buffer solutions. Medically, sodium acetate is important component as an electrolyte replenisher when given intravenously. It is mainly indicated to correct sodium levels in hyponatremic patients. It can be used also in metabolic acidosis and for urine alkalinization.

Indication

Injection, USP 40 mEq is indicated as a source of sodium, for addition to large volume intravenous fluids to prevent or correct hyponatremia in patients with restricted or no oral intake. It is also useful as an additive for preparing specific intravenous fluid formulas when the needs of the patient cannot be met by standard electrolyte or nutrient solutions. Sodium acetate and other bicarbonate precursors are alkalinising agents, and can be used to correct metabolic acidosis, or for alkalinisation of the urine.

Associated Conditions

  • Hyponatremia
  • Hypovolaemia
  • Mild, moderate Metabolic Acidosis

FDA Approved Products

BSS
Manufacturer:Alcon Laboratories, Inc.
Route:OPHTHALMIC
Strength:3.9 mg in 1 mL
Approved: 2016/01/28
NDC:0065-0795
Physiosol
Manufacturer:ICU Medical Inc.
Route:IRRIGATION
Strength:222 mg in 100 mL
Approved: 2022/01/06
NDC:0990-6141
Balanced Salt
Manufacturer:B. Braun Medical Inc.
Route:IRRIGATION
Strength:3.9 mg in 1 mL
Approved: 2022/02/22
NDC:0264-1945
Isolyte S pH 7.4
Manufacturer:B. Braun Medical Inc.
Route:INTRAVENOUS
Strength:0.37 g in 100 mL
Approved: 2023/10/06
NDC:0264-7707
Balanced Salt
Manufacturer:B. Braun Medical Inc.
Route:IRRIGATION
Strength:3.9 mg in 1 mL
Approved: 2022/02/21
NDC:0264-2514

Singapore Approved Products

GELASPAN SOLUTION FOR INFUSION
Manufacturer:B. Braun Medical SA (equivalent to B. Braun Medical AG)
Form:INFUSION, SOLUTION
Strength:3.27g/1000ml
Online:Yes
Approved: 2017/10/04
Approval:SIN15336P
AMINOPLASMAL B.BRAUN 10% E SOLUTION FOR INFUSION
Manufacturer:B. Braun Melsungen AG
Form:INFUSION, SOLUTION
Strength:2.858g/1000ml
Online:Yes
Approved: 2018/01/23
Approval:SIN15411P
SmofKabiven Peripheral Emulsion for Infusion
Manufacturer:Fresenius Kabi AB
Form:INJECTION, EMULSION
Strength:5.62g /1000ml
Online:Yes
Approved: 2013/01/08
Approval:SIN14287P
OLICLINOMEL N7-1000 E EMULSION FOR INFUSION
Manufacturer:BAXTER SA, Ajinomoto North America Incorporated (Intermediate)
Form:EMULSION
Strength:2.45 g/l
Online:Yes
Approved: 2004/05/06
Approval:SIN12539P
PLASMA-LYTE A INJECTION
Manufacturer:Baxter Healthcare Corporation
Form:INJECTION
Strength:368 mg/100 ml
Online:Yes
Approved: 1991/08/19
Approval:SIN06523P

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