MedPath

Prazosin

Generic Name
Prazosin
Brand Names
Minipress, Minizide
Drug Type
Small Molecule
Chemical Formula
C19H21N5O4
CAS Number
19216-56-9
Unique Ingredient Identifier
XM03YJ541D

Overview

Prazosin is a drug used to treat hypertension. Prazosin is marketed by Pfizer and was initially approved by the FDA in 1988. It belongs to the class of drugs known as alpha-1 antagonists. Recently, many studies have evaluated the benefits of this drug in controlling the symptoms of post-traumatic stress disorder (PTSD) and associated nightmares.

Background

Prazosin is a drug used to treat hypertension. Prazosin is marketed by Pfizer and was initially approved by the FDA in 1988. It belongs to the class of drugs known as alpha-1 antagonists. Recently, many studies have evaluated the benefits of this drug in controlling the symptoms of post-traumatic stress disorder (PTSD) and associated nightmares.

Indication

This drug is indicated for the treatment of hypertension (high blood pressure). Prazosin can be given alone or given with other blood pressure-lowering drugs, including diuretics or beta-adrenergic blocking agents . Prazosin does not negatively impact lung function, and therefore may be used to manage hypertension in patients who are asthmatic or patients with chronic obstructive lung disease (COPD).

Associated Conditions

  • Agitation
  • Benign Prostatic Hyperplasia (BPH)
  • Hypertension
  • Raynaud's Phenomenon
  • Disturbed sleep/nightmares

FDA Approved Products

prazosin hydrochloride
Manufacturer:Lifestar Pharma LLC
Route:ORAL
Strength:2 mg in 1 1
Approved: 2023/03/17
NDC:70756-430
Prazosin Hydrochloride
Manufacturer:Bryant Ranch Prepack
Route:ORAL
Strength:1 mg in 1 1
Approved: 2022/07/01
NDC:71335-1724
Prazosin Hydrochloride
Manufacturer:Mylan Institutional Inc.
Route:ORAL
Strength:1 mg in 1 1
Approved: 2023/04/03
NDC:51079-630
Prazosin Hydrochloride
Manufacturer:Aphena Pharma Solutions - Tennessee, LLC
Route:ORAL
Strength:1 mg in 1 1
Approved: 2023/03/20
NDC:71610-693
Minipress
Manufacturer:Pfizer Laboratories Div Pfizer Inc
Route:ORAL
Strength:5 mg in 1 1
Approved: 2023/09/07
NDC:0069-4380

Singapore Approved Products

APO-PRAZO TABLET 2 mg
Manufacturer:APOTEX INC
Form:TABLET
Strength:2 mg
Online:Yes
Approved: 1992/11/25
Approval:SIN07260P
MINISON TABLET 1MG
Manufacturer:Y.S.P. Industries (M) Sdn. Bhd.
Form:TABLET
Strength:1mg
Online:Yes
Approved: 2021/03/18
Approval:SIN16122P
APO-PRAZO TABLET 1 mg
Manufacturer:APOTEX INC
Form:TABLET
Strength:1 mg
Online:Yes
Approved: 1992/11/25
Approval:SIN07264P
APO-PRAZO TABLET 5 mg
Manufacturer:APOTEX INC
Form:TABLET
Strength:5 mg
Online:Yes
Approved: 1992/11/25
Approval:SIN07263P
ATODEL 1 TABLET 1 mg
Manufacturer:REMEDICA LTD
Form:TABLET
Strength:1 mg
Online:Yes
Approved: 1993/10/26
Approval:SIN07529P

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