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Becaplermin

Generic Name
Becaplermin
Brand Names
Regranex
Drug Type
Biotech
CAS Number
165101-51-9
Unique Ingredient Identifier
1B56C968OA
Background

Becaplermin is produced by recombinant DNA technology by insertion of the gene for the B chain of platelet derived growth factor (PDGF) into the yeast, Saccharomyces cerevisiae. Becaplermin has a molecular weight of approximately 25 KD and is a homodimer composed of two identical polypeptide chains that are bound together by disulfide bonds.

Indication

For topical treatment of skin ulcers (from diabetes)

Associated Conditions
Skin Ulcer

TheraGauze™ Alone and Regranex®Gel 0.01% Plus TheraGauze™ in the Treatment of Wagner Stage I Diabetic Foot Ulcers

Not Applicable
Conditions
Diabetic Foot Ulcer
Interventions
Device: TheraGauze
First Posted Date
2006-10-19
Last Posted Date
2008-05-07
Lead Sponsor
Solsys Medical LLC
Target Recruit Count
30
Registration Number
NCT00389636
Locations
🇺🇸

Northwestern University, Chicago, Illinois, United States

A Study on the Efficacy and Safety of Long-Term Treatment and Re-Treatment of Lower Extremity Diabetic Ulcers With REGRANEX

Phase 3
Terminated
Conditions
Foot Ulcer
Diabetic Foot
Skin Ulcer
Diabetic Neuropathies
First Posted Date
2002-05-03
Last Posted Date
2011-06-08
Lead Sponsor
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Target Recruit Count
84
Registration Number
NCT00034788
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