Overview
Phenoxyethanol is a colorless liquid with a pleasant odor. It is a glycol ether used as a perfume fixative, insect repellent, antiseptic, solvent, preservative, and also as an anesthetic in fish aquaculture. Phenoxyethanol is an ether alcohol with aromatic properties. It is both naturally found and manufactured synthetically. Demonstrating antimicrobial ability, phenoxyethanol acts as an effective preservative in pharmaceuticals, cosmetics and lubricants . Phenoxyethanol (EU), or PE, is the most commonly used globally-approved preservative in personal care formulations. It is very easy to use in various types of formulations and is chemically stable. Phenoxyethanol is a colorless, clear, oily liquid with a faint aromatic odor at room temperature and a low water solubility and evaporation rate. It is produced by reacting phenol (EU) and ethylene oxide (EU) at a high temperature and pressure. This substance occurs naturally in green tea (EU) . According to the European Union Cosmetics Regulation (EC) n.1223/2009, phenoxyethanol is authorized as a preservative in cosmetic formulations at a maximum concentration of 1.0% . Phenoxyethanol has been classified as an antimicrobial and preservative by Health Canada . It has also been used in vaccines and shown to inactivate bacteria, and several types of yeast .
Indication
Antimicrobial agent used as a preservative in cosmetics , , .
Associated Conditions
No associated conditions information available.
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|
No clinical trials found
No clinical trials found for this drug
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| SHENZHEN BENLIJU BIO-TECH CO.,LTD | 84449-006 | TOPICAL | 0.01 g in 1.5 g | 4/28/2025 |
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No HSA approvals found for this drug. | |||||
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| No NMPA approvals found for this drug. | |||||
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| No PPB approvals found for this drug. | |||||
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| OCTENISEPT octenidine hydrochloride 1mg/mL, phenoxyethanol 20mg/mL topical solution spray bottle (50mL) | 352595 | Medicine | A | 1/6/2021 | |
| OCTENISEPT octenidine hydrochloride 1mg/mL, phenoxyethanol 20mg/mL solution bottle | 338418 | Medicine | A | 6/26/2020 |
Health Canada Drug Approvals
Approved Product | Company | DIN | Dosage Form | Strength | Market Date |
|---|---|---|---|---|---|
| MARCORODEX | rougier pharma division of ratiopharm inc | 02229710 | Liquid - Topical | 1 G / 100 ML | 12/10/1996 |
| GRIME EATER LOTION SOAP 2.5% | grime eater products ltd. | 00765406 | Soap Bar - Topical | 2.5 % | 12/31/1988 |
| ACROPOLE BLEU | groupe parall inc | 02137836 | Jelly - Topical | .45 % | 10/1/1997 |
| COSMOS HV | groupe parall inc | 02136988 | Liquid - Topical | .45 % | 12/18/1996 |
| MICRO | groupe parall inc | 02136996 | Gel - Topical | .45 % | 10/15/1997 |
| LANOHEX SHP 1.7% | rougier pharma division of ratiopharm inc | 00489255 | Shampoo - Topical | 1.7 % | 12/31/1960 |
| LANOHEX NETTOYEUR POUR LA PEAU 1.7% | rougier pharma division of ratiopharm inc | 00489263 | Liquid - Topical | 1.7 % | 12/31/1960 |
CIMA AEMPS Drug Approvals
Approved Product | Company | Registration Number | Pharmaceutical Form | Prescription Type | Status |
|---|---|---|---|---|---|
| No CIMA AEMPS (Spain) approvals found for this drug. | |||||
Philippines FDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Philippines FDA approvals found for this drug. | |||||
Saudi SFDA Drug Approvals
Approved Product | Company | License Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Saudi SFDA approvals found for this drug. | |||||
Malaysia NPRA Drug Approvals
Approved Product | Company | Registration Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No Malaysia NPRA approvals found for this drug. | |||||
UK EMC Drug Information
Medicine Name | MA Holder | MA Number | Pharmaceutical Form | Active Ingredient | Authorization Date |
|---|---|---|---|---|---|
| No UK EMC drug information found for this drug. | |||||
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