Nitroglycerin
- Generic Name
- Nitroglycerin
- Brand Names
- Gonitro, Minitran, Mylan-nitro, Nitro-bid, Nitro-dur, Nitroject, Nitrolingual, Nitromist, Nitrostat, Rectiv, Trinipatch
- Drug Type
- Small Molecule
- Chemical Formula
- C3H5N3O9
- CAS Number
- 55-63-0
- Unique Ingredient Identifier
- G59M7S0WS3
- Background
Nitroglycerin, also known as glyceryl trinitrate, is an organic nitrate and a vasodilating agent that was first discovered in 1847. Originally used to dynamite, its antianginal effects were identified in the late 1860s after it produced headaches in factory workers while workers with angina pectoris or heart failure experienced relief from chest pain. Its u...
- Indication
Sublingual nitroglycerin is indicated for the acute relief of an attack or acute prophylaxis of angina pectoris due to coronary artery disease. Transdermal nitroglycerin is indicated for the prevention of angina pectoris due to coronary artery disease.
...
- Associated Conditions
- Angina Attacks, Angina Pectoris, Congestive Heart Failure (CHF), Perioperative Hypertension, Moderate to severe pain
- Associated Therapies
- -
Perfusion and Antihypertensive Therapy in Acute Ischemic Stroke
- First Posted Date
- 2014-12-30
- Last Posted Date
- 2017-10-26
- Lead Sponsor
- University of Alberta
- Target Recruit Count
- 65
- Registration Number
- NCT02327793
- Locations
- 🇨🇦
University of Alberta, Edmonton, Alberta, Canada
Efficacy and Safety Study of Guanxin Shutong Capsule to Treat Chronic Stable Angina
- Conditions
- Interventions
- First Posted Date
- 2014-11-02
- Last Posted Date
- 2014-11-02
- Lead Sponsor
- Shaanxi Buchang Pharmaceutical Co., Ltd
- Target Recruit Count
- 300
- Registration Number
- NCT02280850
- Locations
- 🇨🇳
The General Hospital of Shenyang Military Region, Shenyang, Liaoning, China
Prevention and Comparison of Different Forms of Administration of Nitrates in the Risk of Radial Spasm During Coronary Angiography.
- Conditions
- Interventions
- First Posted Date
- 2014-10-07
- Last Posted Date
- 2014-10-07
- Lead Sponsor
- Brugmann University Hospital
- Target Recruit Count
- 442
- Registration Number
- NCT02258620
- Locations
- 🇧🇪
CHU-Brugmann, Bruxelles, Belgium
Effects of Nicorandil on Angina Symptoms in Patients With Coronary Slow Flow
- Conditions
- Interventions
- First Posted Date
- 2014-10-01
- Last Posted Date
- 2015-03-31
- Lead Sponsor
- Mashhad University of Medical Sciences
- Target Recruit Count
- 54
- Registration Number
- NCT02254252
Phosphate Lowering in CKD Trial
- First Posted Date
- 2014-08-06
- Last Posted Date
- 2022-08-26
- Lead Sponsor
- VA Office of Research and Development
- Target Recruit Count
- 66
- Registration Number
- NCT02209636
- Locations
- 🇺🇸
Rocky Mountain Regional VA Medical Center, Aurora, CO, Aurora, Colorado, United States
GOT-IT Trial: Glyceryl Trinitrate for Retained Placenta
- Conditions
- Interventions
- First Posted Date
- 2014-03-12
- Last Posted Date
- 2018-05-21
- Lead Sponsor
- University of Edinburgh
- Target Recruit Count
- 1107
- Registration Number
- NCT02085213
- Locations
- 🇬🇧
Royal Infirmary of Edinburgh, Edinburgh, Midlothian, United Kingdom
Anesthetic Advantages of Dexmedetomidine for Hypotensive Anesthesia
- Conditions
- Interventions
- First Posted Date
- 2014-03-11
- Last Posted Date
- 2014-03-11
- Lead Sponsor
- Mahidol University
- Target Recruit Count
- 40
- Registration Number
- NCT02083055
- Locations
- 🇹🇭
Faculty of dentistry, Mahidol university, Rajthevi, Bangkok, Thailand
The Mechanisms of Diameter Changes in Retinal Vessels During Hypoxia
- Conditions
- Interventions
- First Posted Date
- 2014-02-11
- Last Posted Date
- 2015-08-19
- Lead Sponsor
- University of Aarhus
- Target Recruit Count
- 20
- Registration Number
- NCT02059018
- Locations
- 🇩🇰
Department of Ophtalmology, Aarhus University Hospital, Aarhus, Denmark
Study to Evaluate Hemodynamic Response to to a Sublingual Dose of Glyceryl Trinitrate in Subjects Receiving TA-1790, Sildenafil Citrate, and Placebo
- Conditions
- Interventions
- First Posted Date
- 2012-06-11
- Last Posted Date
- 2012-06-14
- Lead Sponsor
- VIVUS LLC
- Target Recruit Count
- 106
- Registration Number
- NCT01616485
- Locations
- 🇺🇸
MDS Pharma Services, Phoenix, Arizona, United States
Esmolol or Nitroglycerin Infusion for Blood Pressure Control Prior to Cardiopulmonary Bypass (CPB) in Cardiac Surgery
- First Posted Date
- 2010-10-01
- Last Posted Date
- 2019-03-01
- Lead Sponsor
- Loma Linda University
- Target Recruit Count
- 70
- Registration Number
- NCT01212874
- Locations
- 🇺🇸
Loma Linda University, Loma Linda, California, United States
Drug Development Updates
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