Capmatinib
- Generic Name
- Capmatinib
- Brand Names
- Tabrecta
- Drug Type
- Small Molecule
- Chemical Formula
- C23H17FN6O
- CAS Number
- 1029712-80-8
- Unique Ingredient Identifier
- TY34L4F9OZ
- Background
Capmatinib is a small molecule kinase inhibitor targeted against c-Met (a.k.a. hepatocyte growth factor receptor [HGFR]), a receptor tyrosine kinase that, in healthy humans, activates signaling cascades involved in organ regeneration and tissue repair. Aberrant c-Met activation - via mutations, amplification, and/or overexpression - is known to occur in many...
- Indication
用于治疗局部晚期或转移性MET外显子14跳跃（METEX 14）突变的非小细胞肺癌（NSCLC）患者。
- Associated Conditions
- Metastatic Non-Small Cell Lung Cancer, Unresectable, locally advanced Non-Small Cell Lung Carcinoma (NSCLC)
- Associated Therapies
- -
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