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A macrolide antibiotic that is similar to erythromycin.
A macrolide antibiotic that is similar to erythromycin.
As a macrolide, troleandomycin binds to the 50S subunit of the bacterial ribosome . This binding inhibits translocation of tRNA along the A, P, and E sites of the ribosome. With tRNA unable to move from site to site, amino acids cannot be deposited onto the polypeptide chain leading to failure of protein synthesis. Bacterial cell growth and duplication is inhibited without the ability to generate the necessary proteins.
For the treatment of bacterial infection.
