Midazolam

Generic Name
Midazolam
Brand Names
Buccolam, Busulfex, Nayzilam, Seizalam
Drug Type
Small Molecule
Chemical Formula
C18H13ClFN3
CAS Number
59467-70-8
Unique Ingredient Identifier
R60L0SM5BC
Background

Midazolam is a short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and amnesic properties. It belongs to a class of drugs called benzodiazepines. This drug is unique from others in this class due to its rapid onset of effects and short duration of action. Midazolam is available by oral, rectal, intranasal...

Indication

Midazolam has different indications depending on its formulation by the FDA.

Nasal
...

Associated Conditions
Epileptic seizure, Status Epilepticus
Associated Therapies
Anaesthesia, Anxiolytic therapy therapy, Sedation for mechanically-ventilated patients, Preoperative amnesia therapy, Preoperative sedation therapy

Combined Ketamine and Midazolam for Generalized Convulsive Status Epilepticus

First Posted Date
2023-03-22
Last Posted Date
2024-10-29
Lead Sponsor
Sohag University
Target Recruit Count
144
Registration Number
NCT05779657
Locations
🇪🇬

Sohag University Hospital, Sohag, Egypt

Drug Interaction Assessment of GSK3882347 in Healthy Participants Aged 18 to 65 Years

Phase 1
Completed
Conditions
Interventions
First Posted Date
2023-03-08
Last Posted Date
2024-11-07
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
27
Registration Number
NCT05760261
Locations
🇬🇧

GSK Investigational Site, Cambridge, United Kingdom

Sedative Effect and Safety of Remimazolam Besylate in ARDS Patients

First Posted Date
2023-03-07
Last Posted Date
2024-03-13
Lead Sponsor
Zhiming Jiang
Target Recruit Count
100
Registration Number
NCT05758597
Locations
🇨🇳

Department of Intensive Care Medicine, Jinan, Shandong, China

A Study to Compare How Different Substances (Caffeine, Warfarin, Omeprazole, Metoprolol, and Midazolam) Are Handled by the Body of Healthy People and People With Liver Cirrhosis

First Posted Date
2023-02-23
Last Posted Date
2024-11-18
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
30
Registration Number
NCT05741385
Locations
🇩🇪

CRS Clinical Research Services Mannheim GmbH, Mannheim, Germany

A Study in Healthy Men to Test How Well Multiple Doses of BI 1839100 Are Tolerated and How BI 1839100 Influences the Amount of Other Medicines in the Blood

First Posted Date
2023-02-22
Last Posted Date
2024-11-13
Lead Sponsor
Boehringer Ingelheim
Target Recruit Count
67
Registration Number
NCT05738291
Locations
🇳🇱

ICON-Groningen-62040, Groningen, Netherlands

Comparison of Remimazolam and Midazolam for Preventing Intraoperative Nausea and Vomiting During Cesarean Section Under Spinal Anesthesia

First Posted Date
2023-02-21
Last Posted Date
2024-02-06
Lead Sponsor
Yonsei University
Target Recruit Count
80
Registration Number
NCT05736341
Locations
🇰🇷

Yonsei University Health System, Severance Hospital, Seoul, Korea, Republic of

Enhancing Week-long Psychological Treatment for PTSD With Ketamine

Phase 2
Recruiting
Conditions
Interventions
First Posted Date
2023-02-21
Last Posted Date
2024-11-11
Lead Sponsor
Yale University
Target Recruit Count
162
Registration Number
NCT05737693
Locations
🇮🇱

Tel Aviv University, Tel Aviv, Israel

🇺🇸

Yale University School of Medicine, New Haven, Connecticut, United States

A Study of Milvexian in Healthy Adult Females

First Posted Date
2023-01-31
Last Posted Date
2023-08-18
Lead Sponsor
Janssen Pharmaceutica N.V., Belgium
Target Recruit Count
20
Registration Number
NCT05706753
Locations
🇧🇪

SGS Belgium NV, Edegem, Belgium

Study of Potential CYP3A4 Induction by INDV-2000 in Healthy Adults

Phase 1
Completed
Conditions
Interventions
First Posted Date
2023-01-23
Last Posted Date
2024-05-28
Lead Sponsor
Indivior Inc.
Target Recruit Count
20
Registration Number
NCT05694533
Locations
🇺🇸

Celerion, Tempe, Arizona, United States

Effect of Sedative and Anxiolytic Premedication on Children Experience After General Anesthesia

Phase 3
Recruiting
Conditions
Interventions
First Posted Date
2023-01-12
Last Posted Date
2024-12-16
Lead Sponsor
University Hospital, Montpellier
Target Recruit Count
1000
Registration Number
NCT05681572
Locations
🇫🇷

Uhmontpellier, Montpellier, France

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