MedPath

Propofol

Generic Name
Propofol
Brand Names
Diprivan
Drug Type
Small Molecule
Chemical Formula
C12H18O
CAS Number
2078-54-8
Unique Ingredient Identifier
YI7VU623SF

Overview

Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness, nausea, vomiting) than with thiopental, methohexital, and etomidate. Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries.

Background

Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness, nausea, vomiting) than with thiopental, methohexital, and etomidate. Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries.

Indication

Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.

Associated Conditions

No associated conditions information available.

FDA Approved Products

PROPOFOL
Manufacturer:HF Acquisition Co LLC, DBA HealthFirst
Route:INTRAVENOUS
Strength:10 mg in 1 mL
Approved: 2022/12/09
NDC:51662-1293
PROPOFOL
Manufacturer:HF Acquisition Co LLC, DBA HealthFirst
Route:INTRAVENOUS
Strength:10 mg in 1 mL
Approved: 2020/02/23
NDC:51662-1471
Propofol Lipuro
Manufacturer:B. Braun Medical Inc.
Route:INTRAVENOUS
Strength:10 mg in 1 mL
Approved: 2021/12/20
NDC:0264-4850
propofol
Manufacturer:NorthStar Rx LLC
Route:INTRAVENOUS
Strength:10 mg in 1 mL
Approved: 2022/11/17
NDC:16714-977
Propofol
Manufacturer:Pfizer Laboratories Div Pfizer Inc
Route:INTRAVENOUS
Strength:10 mg in 1 mL
Approved: 2023/03/07
NDC:0069-0234

Singapore Approved Products

Recofol N 10mg/ml Emulsion for injection or infusion
Manufacturer:B.Braun Melsungen AG
Form:INJECTION
Strength:10 mg/ml
Online:Yes
Approved: 1996/07/03
Approval:SIN08801P
Propofol-Lipuro 2% (20mg/ml)
Manufacturer:B. Braun Melsungen AG
Form:EMULSION
Strength:20.0mg/ml
Online:Yes
Approved: 2009/03/23
Approval:SIN13622P
FRESOFOL MCT/LCT (PROPOFOL) EMULSION FOR INJECTION OR INFUSION 2%
Manufacturer:FRESENIUS KABI AUSTRIA GMBH
Form:EMULSION
Strength:2%
Online:Yes
Approved: 2003/12/05
Approval:SIN12472P
Recofol N 20mg/ml Emulsion for injection or infusion
Manufacturer:B.Braun Melsungen AG
Form:INJECTION
Strength:20 mg/ml
Online:Yes
Approved: 2002/01/03
Approval:SIN11754P
PROPOFOL-LIPURO INJECTION 1% w/v
Manufacturer:B BRAUN MELSUNGEN AG, B. Braun Melsungen AG
Form:EMULSION
Strength:10 mg/ml
Online:Yes
Approved: 2003/04/25
Approval:SIN12266P

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