Overview
An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
Background
An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.
Indication
用于防治糙皮病等烟酸缺乏病，也用于防治心脏传导阻滞。
Associated Conditions
- Gastrointestinal insufficiency
- Hepatic Insufficiency
- Macrocytic anemia
- Secondary anemia
- Vitamin Deficiency
- Severe debilitation
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2025/07/03 | Not Applicable | Completed | Federal University of Rio Grande do Sul | ||
2024/10/15 | Phase 2 | Recruiting | |||
2024/09/19 | Phase 2 | Recruiting | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | ||
2024/06/20 | Phase 2 | Recruiting | University of Chile | ||
2024/02/28 | Phase 1 | Recruiting | |||
2023/08/23 | Phase 2 | Recruiting | University Hospital, Angers | ||
2023/07/24 | Phase 3 | Completed | KRL Hospital, Islamabad | ||
2023/07/21 | Phase 3 | Recruiting | |||
2023/01/27 | Early Phase 1 | Not yet recruiting | |||
2022/08/24 | Phase 3 | Completed |
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| AvPAK | 50268-677 | ORAL | 20 mg in 1 1 | 4/12/2022 | |
| Sincerus Florida, LLC | 72934-1017 | TOPICAL | 2 g in 100 g | 4/23/2019 | |
| CarWin Pharmaceutical Associates, LLC | 15370-105 | ORAL | 5 mg in 1 1 | 1/10/2024 | |
| Sincerus Florida, LLC | 72934-2166 | TOPICAL | 4 g in 100 g | 5/13/2019 | |
| Sincerus Florida, LLC | 72934-1066 | TOPICAL | 4 g in 100 g | 4/23/2019 | |
| Sincerus Florida, LLC | 72934-1200 | TOPICAL | 4 g in 100 g | 7/2/2020 | |
| Exeltis USA, Inc. | 0642-7473 | ORAL | 15 mg in 1 1 | 2/14/2023 | |
| Marnel Pharmaceuticals, Inc. | 0682-3001 | ORAL | 100 mg in 1 1 | 5/2/2014 | |
| Sincerus Florida, LLC | 72934-5069 | TOPICAL | 4 g in 100 g | 5/22/2019 | |
| Sincerus Florida, LLC | 72934-1088 | TOPICAL | 5 g in 100 g | 5/17/2019 |
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| ENZYPLEX TABLET | SIN06211P | ENTERIC COATED TABLET | 10 mg | 5/3/1991 | |
| CERNEVIT FOR INJECTION | SIN11975P | INJECTION, POWDER, FOR SOLUTION | 46 mg/vial | 6/5/2002 | |
| IBERET-FOLIC-500 TABLET | SIN05447P | TABLET, FILM COATED | 30 mg | 2/19/1991 | |
| TAMIPOOL FOR INJECTION | SIN11849P | INJECTION, POWDER, FOR SOLUTION | 40 mg/vial | 3/15/2002 | |
| SOLUVIT N FOR INFUSION | SIN05209P | INJECTION, POWDER, FOR SOLUTION | 40 mg/vial | 11/14/1990 |
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| Nicotinamide Tablets | 国药准字H44020174 | 化学药品 | 片剂 | 4/7/2020 | |
| Nicotinamide Tablets | 国药准字H42020452 | 化学药品 | 片剂 | 7/13/2020 | |
| Nicotinamide Tablets | 国药准字H35020747 | 化学药品 | 片剂 | 7/13/2020 | |
| Nicotinamide Tablets | 国药准字H14022427 | 化学药品 | 片剂 | 9/9/2020 | |
| Nicotinamide Tablets | 国药准字H20066794 | 化学药品 | 片剂 | 7/15/2020 | |
| Nicotinamide Tablets | 国药准字H62020011 | 化学药品 | 片剂 | 4/10/2020 | |
| Nicotinamide Tablets | 国药准字H14022428 | 化学药品 | 片剂 | 9/9/2020 | |
| Nicotinamide Tablets | 国药准字H22022707 | 化学药品 | 片剂 | 3/11/2020 | |
| Nicotinamide Tablets | 国药准字H41022869 | 化学药品 | 片剂 | 7/20/2020 | |
| Nicotinamide Tablets | 国药准字H41021754 | 化学药品 | 片剂 | 5/6/2020 |
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| MULTIMAX SYRUP | N/A | N/A | N/A | 7/8/2014 | |
| CERNEVIT FOR INJ | N/A | N/A | N/A | 4/18/2008 | |
| BIOCATALIN INJECTABLE SOLN (VET) | N/A | N/A | N/A | 8/9/1984 | |
| BIHAKU TAB | N/A | N/A | N/A | 7/1/1994 | |
| HUAZIN INJ | N/A | N/A | N/A | 4/28/1982 |
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| Cellula-T oral powder jar | 43995 | Hong Sp & Hs | Medicine | A | 4/13/1993 |
| Men's Multi | 326959 | Medicine | A | 12/2/2019 | |
| BLACKMORES SUPERKIDS MULTI CHEWABLES | 289492 | Medicine | A | 5/30/2017 | |
| Super B Complex tablets | 126510 | Medicine | A | 3/28/2006 | |
| BLACKMORES B+C TABLETS | 215811 | Medicine | A | 10/9/2013 | |
| Wealthy Health Bio-Maxi B Excellent Stress Relief Formula with Herbs | 139048 | Medicine | A | 5/21/2007 | |
| Caruso's Hair Food | 130857 | Medicine | A | 8/30/2006 | |
| Berocca Performance Original effervescent tablets | 193893 | Medicine | A | 1/17/2012 | |
| Kids Multi | 329564 | Medicine | A | 2/6/2020 | |
| FAB IRON Liquid Iron | 287563 | Medicine | A | 4/6/2017 |