Nicotinamide

Generic Name
Nicotinamide
Brand Names
Alertonic, Fortaplex, Infuvite, Infuvite Pediatric, Mvc-fluoride, Mvi Pediatric, Natafort, Neo-bex, Nicomide, Pregvit, Tandem Plus
Drug Type
Small Molecule
Chemical Formula
C6H6N2O
CAS Number
98-92-0
Unique Ingredient Identifier
25X51I8RD4
Background

An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.

Indication

用于防治糙皮病等烟酸缺乏病,也用于防治心脏传导阻滞。

Associated Conditions
Gastrointestinal insufficiency, Hepatic Insufficiency, Macrocytic anemia, Secondary anemia, Vitamin Deficiency, Severe debilitation
Associated Therapies
Dietary and Nutritional Therapies, Nutritional supplementation, Dietary supplementation

Nutritional Support and Prophylaxis Doses of Azithromycin for Pregnant Women - Mumta Pregnant Women Trial

First Posted Date
2019-07-09
Last Posted Date
2022-10-13
Lead Sponsor
Vital Pakistan Trust
Target Recruit Count
1884
Registration Number
NCT04012177
Locations
🇵🇰

Peri-urban slum (Rehri Goth), Karachi, Sindh, Pakistan

Skin Cancer Prevention With Nicotinamide in Transplant Recipients - Pilot Trial

First Posted Date
2018-12-07
Last Posted Date
2023-04-06
Lead Sponsor
Women's College Hospital
Target Recruit Count
120
Registration Number
NCT03769285
Locations
🇨🇦

Toronto General Hospital, University Health Network, Toronto, Ontario, Canada

Study of the Efficacy and Safety of Nicotinamide in Patients With Friedreich Ataxia

Phase 2
Withdrawn
Conditions
Interventions
First Posted Date
2018-12-03
Last Posted Date
2024-01-24
Lead Sponsor
RWTH Aachen University
Registration Number
NCT03761511
Locations
🇫🇷

Service de génétique médicale - Hôpital La Pitié Salpetrière, Paris, France

🇦🇹

Medical University Innsbruck, Innsbruck, Austria

🇮🇹

Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy

and more 4 locations

Study of Nicotinamide in Early Onset Preeclampsia

Phase 2
Completed
Conditions
Interventions
First Posted Date
2018-02-01
Last Posted Date
2022-09-08
Lead Sponsor
University of North Carolina, Chapel Hill
Target Recruit Count
23
Registration Number
NCT03419364
Locations
🇺🇸

UNC at Chapel Hill, Chapel Hill, North Carolina, United States

DNA Methylation in Malar Melasma and Its Change by Sunscreen, Retinoic Acid and Niacinamide.

First Posted Date
2018-01-08
Last Posted Date
2018-01-09
Lead Sponsor
Universidad Autonoma de San Luis Potosí
Target Recruit Count
28
Registration Number
NCT03392623

Nicotinamide Treatment for Lupus-associated Skin Lesions in Lupus Erythematosus

First Posted Date
2017-08-24
Last Posted Date
2021-02-02
Lead Sponsor
Second Xiangya Hospital of Central South University
Target Recruit Count
40
Registration Number
NCT03260166
Locations
🇨🇳

The Second Xiangya Hospital of Central South University, Changsha, Hunan, China

Healthy Combine Study

First Posted Date
2017-05-02
Last Posted Date
2024-02-23
Lead Sponsor
Northwestern University
Target Recruit Count
39
Registration Number
NCT03136705
Locations
🇺🇸

Center for Translational Metabolism and Health (CTMH), Northwestern University, Chicago, Illinois, United States

Nicotinamide as an Early Alzheimer's Disease Treatment

First Posted Date
2017-02-23
Last Posted Date
2023-10-17
Lead Sponsor
University of California, Irvine
Target Recruit Count
46
Registration Number
NCT03061474
Locations
🇺🇸

University of California, Irvine, Irvine, California, United States

🇺🇸

University of California, Los Angeles, Los Angeles, California, United States

Anticancer Activity of Nicotinamide on Lung Cancer

First Posted Date
2015-04-15
Last Posted Date
2020-01-27
Lead Sponsor
Il Yeong Park, Ph.D.
Target Recruit Count
110
Registration Number
NCT02416739
Locations
🇰🇷

Chonnam National University Hwasun Hospital, Hwasun, Chonnam, Korea, Republic of

The COMBINE Study: The CKD Optimal Management With BInders and NicotinamidE

First Posted Date
2014-10-07
Last Posted Date
2021-08-02
Lead Sponsor
The Cleveland Clinic
Target Recruit Count
205
Registration Number
NCT02258074
Locations
🇺🇸

NorthShore University Health System, Chicago, Illinois, United States

🇺🇸

Denver Nephrology Research, Denver, Colorado, United States

🇺🇸

Northwestern University, Chicago, Illinois, United States

and more 4 locations
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