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Ethanolamine oleate is a mild sclerosing agent used in the treatment of esophageal varices with recent bleeding episodes.
Ethanolamine oleate is a mild sclerosing agent used in the treatment of esophageal varices with recent bleeding episodes.
The oleic acid component of ethanolamine oleate is responsible for the inflammatory response, and may also activate coagulation in vivo by release of tissue factor and activation of Hageman factor. The ethanolamine component, however, may inhibit fibrin clot formation by chelating calcium, so that a procoagulant action of ethanolamine oleate has not been demonstrated.
For the treatment of patients with esophageal varices that have recently bled, to prevent rebleeding.
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