Trimetazidine

Generic Name
Trimetazidine
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C14H22N2O3
CAS Number
5011-34-7
Unique Ingredient Identifier
N9A0A0R9S8
Background

Trimetazidine is a piperazine derivative indicated for the symptomatic treatment of stable angina pectoris in patients inadequately controlled or intolerant to first line therapies. Trimetazidine has been studied as a treatment for angina pectoris since the late 1960s.
...

Indication

Trimetazidine is indicated for the symptomatic treatment of stable angina pectoris in patients inadequately controlled or intolerant to first line therapies.

Associated Conditions
Angina Pectoris, Chronic Stable Angina Pectoris, Tinnitus, Vertigo, Decreased visual acuity caused by Vascular Disorders
Associated Therapies
-

"The Effect of Trimetazidine on the Clinical Outcome of Acute Ischemic Stroke Patients"

Phase 3
Recruiting
Conditions
Interventions
First Posted Date
2024-10-24
Last Posted Date
2024-10-24
Lead Sponsor
Ain Shams University
Target Recruit Count
60
Registration Number
NCT06656442
Locations
🇪🇬

Ain Shams University Hospital, Cairo, Egypt

Trimetazidine Efficacy in Attenuating Paclitaxel-Induced Peripheral Neuropathy

First Posted Date
2024-06-14
Last Posted Date
2024-11-21
Lead Sponsor
Minia University
Target Recruit Count
60
Registration Number
NCT06459193
Locations
🇪🇬

Minia Oncology Center, Minya, Egypt

Benefits of Trimetazidine in MAFLD Pateints

First Posted Date
2023-11-21
Last Posted Date
2023-11-21
Lead Sponsor
October 6 University
Target Recruit Count
60
Registration Number
NCT06140953
Locations
🇪🇬

Maha Youssif Fekry, Giza, October 6, Egypt

The Effect of Trimetazidine on Mitochondrial Function, Myocardial Performance, and Invasive Hemodynamics in Patients Diagnosed With Wild-Type Transthyretin Cardiac Amyloidosis

First Posted Date
2022-12-01
Last Posted Date
2024-04-25
Lead Sponsor
Steen Hvitfeldt Poulsen
Target Recruit Count
24
Registration Number
NCT05633563
Locations
🇩🇰

Aarhus University Hospital, Department of Cardiology, Aarhus N, Danmark, Denmark

Efficacy of Trimetazidine in Diabetic Patients

First Posted Date
2022-09-27
Last Posted Date
2022-09-27
Lead Sponsor
Ain Shams University
Target Recruit Count
60
Registration Number
NCT05556005
Locations
🇪🇬

Ainshams university hospitals, Cairo, Egypt

The Effects of TMZ on Diabetic Nephropathy

Phase 2
Conditions
Interventions
First Posted Date
2021-12-07
Last Posted Date
2021-12-07
Lead Sponsor
Tongji Hospital
Target Recruit Count
150
Registration Number
NCT05147194

Effect of Trimetazidine on Radiotherapy-induced Heart Damage.

Phase 2
Conditions
Interventions
First Posted Date
2021-06-25
Last Posted Date
2021-06-25
Lead Sponsor
Peking University Third Hospital
Target Recruit Count
80
Registration Number
NCT04939857

Targeting Metabolic Flexibility in Amyotrophic Lateral Sclerosis (ALS)

First Posted Date
2021-03-09
Last Posted Date
2023-07-20
Lead Sponsor
The University of Queensland
Target Recruit Count
21
Registration Number
NCT04788745
Locations
🇬🇧

King's College London, London, United Kingdom

🇦🇺

Royal Brisbane & Women's Hospital, Brisbane, Queensland, Australia

🇳🇱

University Medical Centre Utrecht, Utrecht, Netherlands

Prevention of Acute Myocardial Injury by Trimetazidine in Patients Hospitalized for COVID-19

First Posted Date
2021-02-18
Last Posted Date
2021-02-21
Lead Sponsor
Ministry of Health, Brazil
Target Recruit Count
80
Registration Number
NCT04760821
Locations
🇧🇷

Heart Institute (InCor-HCFMUSP), Sao Paulo, SP, Brazil

Efficacy of Personalized Exercise Program and Trimetazidine in Rehabilitation of Patients After RFA of AF

First Posted Date
2020-08-13
Last Posted Date
2021-06-09
Lead Sponsor
National Research Center for Preventive Medicine
Target Recruit Count
72
Registration Number
NCT04511520
© Copyright 2024. All Rights Reserved by MedPath