Fexofenadine
- Generic Name
- Fexofenadine
- Brand Names
- Allegra, Allegra-D, Mucinex Non-drowsy Allergy, Wal-fex, Telfast
- Drug Type
- Small Molecule
- Chemical Formula
- C32H39NO4
- CAS Number
- 83799-24-0
- Unique Ingredient Identifier
- E6582LOH6V
- Background
Fexofenadine is an over-the-counter second-generation antihistamine used in the treatment of various allergic symptoms. It is selective for the H receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier - this is in contrast to previous first-generation antihistamines, such as diphenhydramine, which readily bind to o...
- Indication
In the United States, fexofenadine is indicated for the symptomatic treatment of allergic rhinitis in patients ≥2 years old and chronic idiopathic urticaria in patients ≥6 months old. In Canada, fexofenadine carries the same indications but is approved only for patients ≥12 years old. Fexofenadine is also available in combination with pseudoephedrine for the...
- Associated Conditions
- Allergic Rhinitis (AR), Chronic Idiopathic Urticaria, Seasonal Allergic Rhinitis
- Associated Therapies
- Antihistamine
Aprepitant in the Management of Biological Therapies-related Severe Pruritus
- First Posted Date
- 2012-09-12
- Last Posted Date
- 2012-09-12
- Lead Sponsor
- Campus Bio-Medico University
- Target Recruit Count
- 45
- Registration Number
- NCT01683552
- Locations
- 🇮🇹
Campus Bio-Medico of Rome University, Roma, Italy
Do Furanocoumarins Mediate the Fexofenadine-grapefruit Juice Interaction?
- First Posted Date
- 2012-02-03
- Last Posted Date
- 2017-05-30
- Lead Sponsor
- University of North Carolina, Chapel Hill
- Target Recruit Count
- 18
- Registration Number
- NCT01526213
- Locations
- 🇺🇸
North Carolina Clinical and Translational Research Center, Chapel Hill, North Carolina, United States
A Study of Onset of Action of Loratadine and Fexofenadine in Participants With Seasonal Allergic Rhinitis (P08712)
- Conditions
- Interventions
- First Posted Date
- 2011-11-10
- Last Posted Date
- 2015-03-11
- Lead Sponsor
- Bayer
- Target Recruit Count
- 255
- Registration Number
- NCT01469234
Effectiveness of Two Preparations of Loratadine + Pseudoephedrine in Patients With Perennial Allergic Rhinitis.
- First Posted Date
- 2010-10-26
- Last Posted Date
- 2016-04-11
- Lead Sponsor
- Azidus Brasil
- Target Recruit Count
- 156
- Registration Number
- NCT01228630
- Locations
- 🇧🇷
Lal Clínica Pesquisa E Desenvolvimento Ltda, Valinhos, Sao Paulo, Brazil
Topical Treatment of Under Eye Dark Circles and Swelling
- First Posted Date
- 2010-07-29
- Last Posted Date
- 2015-02-19
- Lead Sponsor
- The Connecticut Sinus Center, PC
- Target Recruit Count
- 30
- Registration Number
- NCT01172522
- Locations
- 🇺🇸
TKL Research, Paramus, New Jersey, United States
Bioequivalence Study of Dr. Reddy's Laboratories Limited Fexofenadine Hydrochloride 180 mg Tablets Under Fed Conditions
- First Posted Date
- 2010-02-10
- Last Posted Date
- 2010-02-10
- Lead Sponsor
- Dr. Reddy's Laboratories Limited
- Target Recruit Count
- 30
- Registration Number
- NCT01066767
- Locations
- 🇨🇦
Anapharm Inc.,, Sainte-Foy Quebec, Canada
Bioequivalence Study of Dr.Reddy's Fexofenadine Hydrochloride 180 mg Tablets Under Fasting Conditions
- First Posted Date
- 2010-02-10
- Last Posted Date
- 2010-02-10
- Lead Sponsor
- Dr. Reddy's Laboratories Limited
- Target Recruit Count
- 44
- Registration Number
- NCT01066754
- Locations
- 🇨🇦
Anapharm Inc.,, Sainte-Foy Quebec, Canada
The Effect Of PF-03654764 +/- Allegra On Symptoms Of Allergic Rhinitis
- Conditions
- Interventions
- First Posted Date
- 2009-12-16
- Last Posted Date
- 2010-08-17
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 64
- Registration Number
- NCT01033396
- Locations
- 🇨🇦
Pfizer Investigational Site, Kingston, Ontario, Canada
Preference for Clarinex Tablets vs Allegra Tablets in Patients With Seasonal Allergies (P03178)
- Conditions
- Interventions
- First Posted Date
- 2008-11-20
- Last Posted Date
- 2022-02-17
- Lead Sponsor
- Organon and Co
- Target Recruit Count
- 118
- Registration Number
- NCT00794768
Preference for Clarinex Tablets vs. Allegra Tablets in Patients With Seasonal Allergies (Study P03179)
- Conditions
- Interventions
- First Posted Date
- 2008-11-20
- Last Posted Date
- 2022-02-17
- Lead Sponsor
- Organon and Co
- Target Recruit Count
- 122
- Registration Number
- NCT00794248
Drug Development Updates
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