MedPath

Bromelains

Generic Name
Bromelains
Drug Type
Biotech
CAS Number
9001-00-7
Unique Ingredient Identifier
U182GP2CF3

Overview

Bromelain is a protease enzyme derived from the stems of pineapples that is composed of a mixture of different thiol endopeptidases and other components like phosphatase, glucosidase, peroxidase, cellulase, escharase, and several protease inhibitors . It works by selectively inhibiting the biosynthesis of proinflammatory prostaglandins and also has analgesic properties, as well as anticancerous and pro-apoptotic effects. Bromelain holds potential therapeutic effect as a treatment of conditions including angina pectoris, bronchitis, sinusitis, surgical trauma, and osteoarthritis. It is considered as a safe food supplement.

Background

Bromelain is a protease enzyme derived from the stems of pineapples that is composed of a mixture of different thiol endopeptidases and other components like phosphatase, glucosidase, peroxidase, cellulase, escharase, and several protease inhibitors . It works by selectively inhibiting the biosynthesis of proinflammatory prostaglandins and also has analgesic properties, as well as anticancerous and pro-apoptotic effects. Bromelain holds potential therapeutic effect as a treatment of conditions including angina pectoris, bronchitis, sinusitis, surgical trauma, and osteoarthritis. It is considered as a safe food supplement.

Indication

可用于各种原因所致的炎症、水肿、血肿、血栓症如支气管炎、支气管哮喘、急性肺炎、产后乳房充血、乳腺炎、产后血栓性静脉炎、视网膜炎等,与抗菌药物合用治疗关节炎、关节周围炎、蜂窝织炎、小腿溃疡等均有效。眼科用于治疗视网膜炎。

Associated Conditions

  • Swelling

FDA Drug Approvals

Approved Product
Manufacturer
NDC Code
Route
Strength
Effective Date
No FDA approvals found for this drug.

EMA Drug Approvals

Approved Product
Authorization Holder
Status
Issued Date
No EMA approvals found for this drug.

HSA Drug Approvals

Approved Product
Manufacturer
Approval Number
Dosage Form
Strength
Approval Date
No HSA approvals found for this drug.

NMPA Drug Approvals

Approved Product
Company
Approval Number
Drug Type
Dosage Form
Approval Date
Bromelain Enteric-coated Tablets
国药准字H20033908
化学药品
片剂(肠溶片)
8/21/2020
Bromelain Enteric-coated Tablets
国药准字H20003383
化学药品
片剂
6/19/2020
Bromelain Enteric-coated Tablets
国药准字H20003084
化学药品
片剂(肠溶片)
8/21/2020
Bromelain Enteric-coated Tablets
国药准字H20003382
化学药品
片剂
3/13/2020
Bromelain Enteric-coated Tablets
国药准字H45021409
化学药品
片剂
8/16/2020
Bromelain Enteric-coated Tablets
国药准字H20003785
化学药品
片剂
7/14/2020
Bromelains Enteric-coated Capsules
国药准字H45021171
化学药品
胶囊剂
8/16/2020

PPB Drug Approvals

Approved Product
Registration No.
Company
Licence No.
Strength
Registration Date
No PPB approvals found for this drug.

TGA Drug Approvals

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