左旋氨氯地平 (Conjupri)

概览

Levamlodipine is a calcium channel blocker used to treat hypertension.

作用机制

Levamlodipine blocks the transmembrane influx of calcium through L-type calcium channels into the vascular and cardiac smooth muscles resulting in vasodilation and a subsequent decrease in blood pressure. Levamlodipine inhibits calcium influx in vascular smooth muscle to a greater degree than in cardiac muscle, leading to decreased peripheral vascular resistance and lowered blood pressure. In vitro studies have shown a negative inotropic effect but this is unlikely to be clinically relevant.

适应症

Levamlodipine is indicated alone or in combination to treat hypertension in adults and children.

• Hypertension