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Carboprost tromethamine

Generic Name
Carboprost tromethamine
Brand Names
Hemabate
Drug Type
Small Molecule
Chemical Formula
C25H47NO8
CAS Number
58551-69-2
Unique Ingredient Identifier
U4526F86FJ

Overview

A nonsteroidal abortifacient agent that is effective in both the first and second trimesters of pregnancy.

Background

A nonsteroidal abortifacient agent that is effective in both the first and second trimesters of pregnancy.

Indication

For aborting pregnancy between the 13th and 20th weeks of gestation as calculated from the first day of the last normal menstrual period and in the following conditions related to second trimester abortion: 1. Failure of expulsion of the fetus during the course of treatment by another method; 2. Premature rupture of membranes in intrauterine methods with loss of drug and insufficient or absent uterine activity; 3. Requirement of a repeat intrauterine instillation of drug for expulsion of the fetus; 4. Inadvertent or spontaneous rupture of membranes in the presence of a previable fetus and absence of adequate activity for expulsion. Also for the treatment of postpartum hemorrhage due to uterine atony which has not responded to conventional methods of management.

Associated Conditions

  • Unresponsive Postpartum Haemorrhage (PPH) caused by Uterine Atony

FDA Approved Products

CARBOPROST TROMETHAMINE
Manufacturer:Alembic Pharmaceuticals Limited
Route:INTRAMUSCULAR
Strength:250 ug in 1 mL
Approved: 2024/03/15
NDC:46708-777
Hemabate
Manufacturer:Pharmacia & Upjohn Company LLC
Route:INTRAMUSCULAR
Strength:250 ug in 1 mL
Approved: 2022/01/10
NDC:0009-0856
CARBOPROST TROMETHAMINE
Manufacturer:Fresenius Kabi USA, LLC
Route:INTRAMUSCULAR
Strength:250 ug in 1 mL
Approved: 2023/05/05
NDC:65219-579
CARBOPROST TROMETHAMINE
Manufacturer:Caplin Steriles Limited
Route:INTRAMUSCULAR
Strength:250 ug in 1 mL
Approved: 2023/02/22
NDC:65145-132
Carboprost Tromethamine
Manufacturer:ONESOURCE SPECIALTY PHARMA LIMITED
Route:INTRAMUSCULAR
Strength:250 ug in 1 mL
Approved: 2023/08/01
NDC:83270-002

Singapore Approved Products

HEMABATE INJECTION 250 mcg/ml
Manufacturer:Pharmacia & Upjohn LLC
Form:INJECTION
Strength:250 mcg/ml
Online:Yes
Approved: 1991/11/29
Approval:SIN06722P

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