Entacapone
- Generic Name
- Entacapone
- Brand Names
- Comtan, Comtess, Stalevo, Entacapone Orion, Entacapone Teva
- Drug Type
- Small Molecule
- Chemical Formula
- C14H15N3O5
- CAS Number
- 130929-57-6
- Unique Ingredient Identifier
- 4975G9NM6T
- Background
Entacapone is a selective, reversible catechol-O-methyl transferase (COMT) inhibitor for the treatment of Parkinson's disease. It is a member of the class of nitrocatechols. When administered concomittantly with levodopa and a decarboxylase inhibitor (e.g., carbidopa), increased and more sustained plasma levodopa concentrations are reached as compared to the...
- Indication
Used as an adjunct to levodopa / carbidopa in the symptomatic treatment of patients with idiopathic Parkinson's Disease who experience the signs and symptoms of end-of-dose "wearing-off".
- Associated Conditions
- Parkinson's Disease (PD), Wearing Off Effect
- Associated Therapies
- -
No news found
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.
© Copyright 2024. All Rights Reserved by MedPath